Results 161 to 170 of about 865,085 (290)

ETV4 interacts with LOXL2 to induce epigenetic activation of NID1 during colorectal cancer progression [PDF]

Tinghui Jiang, Xin Liu, Hao Liu, Kailong Du, Sen Wang, Hui Fan, Ying E. Zhang, Lin Cui, Hewei Zhang, Chun‐Dong Zhang, Yong Xia Zhu, Zhongyu Liu, Youquan Bu, Yunlong Lei   +13 more
openalex   +1 more source

Targeting Oncogenic Transcriptional Networks in Neuroblastoma: From N-Myc to Epigenetic Drugs [PDF]

, 2021
Roberto Ciaccio, Piergiuseppe De Rosa, Sara Aloisi, Marta Viggiano, Leonardo Cimadom, Suleman Khan Zadran, Giovanni Perini, Giorgio Milazzo   +7 more
openalex   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Bisulfite Conversion of DNA: Performance Comparison of Different Kits and Methylation Quantitation of Epigenetic Biomarkers that Have the Potential to Be Used in Non-Invasive Prenatal Testing

, 2015
Chrysanthia A. Leontiou, Michael D. Hadjidaniel, Petros Mina, Pavlos Antoniou, Marios Ioannides, Philippos C. Patsalis   +5 more
openalex   +2 more sources

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Pan-Epigenetic Age Prediction in Mammals. [PDF]

Aging Cell
Koch Z, Li A, Ideker T.
europepmc   +1 more source

Epigenetic modification and a role for the E3 ligase RNF40 in cancer development and metastasis [PDF]

, 2020
Junjiang Fu, Li Liao, Kyathegowdanadoddi Srinivasa Balaji, Chunli Wei, Jaehoon Kim, Jiangzhou Peng   +5 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Astronauts as a Human Aging Model: Epigenetic Age Responses to Space Exposure. [PDF]

Aging Cell
Fuentealba M, Kim J, Hirschberg JW, Shirah B, Overbey EG, Mason C, Furman D.   +6 more
europepmc   +1 more source

<p>Epigenetics mechanisms mediate the miR-125a/BRMS1 axis to regulate invasion and metastasis in gastric cancer</p>

, 2019
Jianbo Xiong, Yi Tu, Zongfeng Feng, Daojiang Li, Zhouwen Yang, Qiuxia Huang, Zhengrong Li, Yi Cao, Zhigang Jie   +8 more
openalex   +2 more sources