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Epigenetics and atherosclerosis
Biochimica et Biophysica Acta (BBA) - General Subjects, 2009The contribution of epigenetic mechanisms to cardiovascular diseases remains poorly understood. Hypomethylation of genomic DNA is present in human atherosclerotic lesions and methylation changes also occur at the promoter level of several genes involved in the pathogenesis of atherosclerosis, such as extracellular superoxide dismutase, estrogen ...
Mikko P, Turunen +2 more
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2021
Aggression is a complex behavioral trait modulated by both genetic and environmental influences on gene expression. By controlling gene expression in a reversible yet potentially lasting manner in response to environmental stimulation, epigenetic mechanisms represent prime candidates in explaining both individual differences in aggression and the ...
Florian, Duclot, Mohamed, Kabbaj
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Aggression is a complex behavioral trait modulated by both genetic and environmental influences on gene expression. By controlling gene expression in a reversible yet potentially lasting manner in response to environmental stimulation, epigenetic mechanisms represent prime candidates in explaining both individual differences in aggression and the ...
Florian, Duclot, Mohamed, Kabbaj
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Psychiatry Research, 2021
Schizophrenia (SCZ) is a chronic psychotic disorder that contributes significantly to disability, affecting behavior, thought, and cognition. It has long been known that there is a heritable component to schizophrenia; studies in both the pre-genomic and post-genomic era, however, have failed to elucidate fully the genetic basis for this complex ...
Anil, Srivastava +7 more
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Schizophrenia (SCZ) is a chronic psychotic disorder that contributes significantly to disability, affecting behavior, thought, and cognition. It has long been known that there is a heritable component to schizophrenia; studies in both the pre-genomic and post-genomic era, however, have failed to elucidate fully the genetic basis for this complex ...
Anil, Srivastava +7 more
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Pancreatology, 2007
'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed.
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'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed.
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Current Opinion in Lipidology, 2020
Purpose of review Studies have shown the three-member paraoxonase (PON) multigene family to be involved in the development of a large variety of diseases with an inflammatory component. Environmental factors such as lifestyle-related factors differ widely between populations and it is important to consider that their impacts ...
Abdolkarim, Mahrooz, Mike, Mackness
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Purpose of review Studies have shown the three-member paraoxonase (PON) multigene family to be involved in the development of a large variety of diseases with an inflammatory component. Environmental factors such as lifestyle-related factors differ widely between populations and it is important to consider that their impacts ...
Abdolkarim, Mahrooz, Mike, Mackness
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Journal of the European Academy of Dermatology and Venereology, 2011
AbstractIncreasing evidence indicates that epigenetic mechanisms are involved in the pathogenesis of autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The pathogenesis of the organ‐specific autoimmune disease psoriasis, however, remains poorly understood.
P, Zhang, Y, Su, Q, Lu
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AbstractIncreasing evidence indicates that epigenetic mechanisms are involved in the pathogenesis of autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The pathogenesis of the organ‐specific autoimmune disease psoriasis, however, remains poorly understood.
P, Zhang, Y, Su, Q, Lu
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WIREs Systems Biology and Medicine, 2016
Why do we grow up to have the traits we do? Most 20th century scientists answered this question by referring only to our genes and our environments. But recent discoveries in the emerging field of behavioral epigenetics have revealed factors at the interface between genes and environments that also play crucial roles in development.
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Why do we grow up to have the traits we do? Most 20th century scientists answered this question by referring only to our genes and our environments. But recent discoveries in the emerging field of behavioral epigenetics have revealed factors at the interface between genes and environments that also play crucial roles in development.
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2014
Among different mechanisms that could lead to interindividual differences in obesity susceptibility, epigenetics has emerged, in the last years, as a potentially very important contributor. The role of epigenetics in obesity may be considered by different points of view.
FRISO, Simonetta, Sang Woon Choi
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Among different mechanisms that could lead to interindividual differences in obesity susceptibility, epigenetics has emerged, in the last years, as a potentially very important contributor. The role of epigenetics in obesity may be considered by different points of view.
FRISO, Simonetta, Sang Woon Choi
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Differentiation, 1979
The nature of the genetic control of pattern formation in development is a major unsolved problem. The analysis of transdetermination phenomena in Drosophila by S. Kauffman has raised the possibility that the controlling principle is not of the obvious ‘one controlling gene-one pattern element’ type, but involves combinatorial coding, with a given ...
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The nature of the genetic control of pattern formation in development is a major unsolved problem. The analysis of transdetermination phenomena in Drosophila by S. Kauffman has raised the possibility that the controlling principle is not of the obvious ‘one controlling gene-one pattern element’ type, but involves combinatorial coding, with a given ...
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2013
Asthma is the most common chronic disease of childhood, and a growing body of evidence indicates that epigenetic variations may mediate the effects of environmental exposures on the development and natural history of asthma. Epigenetics is the study of mitotically or meiotically heritable changes in gene expression that occur without directly altering ...
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Asthma is the most common chronic disease of childhood, and a growing body of evidence indicates that epigenetic variations may mediate the effects of environmental exposures on the development and natural history of asthma. Epigenetics is the study of mitotically or meiotically heritable changes in gene expression that occur without directly altering ...
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