Results 211 to 220 of about 849,922 (340)

PB2480: LENTIVIRAL LABELING OF STROMAL LAYER OF LONG-TERM BONE MARROW CULTURE DEMONSTRATED INEFFICIENCY FOR MESENCHYMAL STEM CELLS AND CONTRIBUTION OF NON-STEM CELLS TO HEMATOPOIETIC ECTOPIC FOCUS IN MICE

HemaSphere, 2023
Dmitriy Karpenko, Aleksei Bigildeev
doaj   +1 more source

Beyond the DNA sequence: mapping the dynamic epigenetic landscape for risk stratification and therapeutic intervention in acute myeloid leukemia. [PDF]

Clin Exp Med
Xie J, Soleimani Samarkhazan H.
europepmc   +1 more source

The lemon genome and DNA methylome unveil epigenetic regulation of citric acid biosynthesis during fruit development [PDF]

Hang Yu, Chao Zhang, Chuang Lu, Yana Wang, Congcong Ge, Gui‐Xiang Huang, Haifeng Wang   +6 more
openalex   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Advancing Epigenetic Combination Therapy in Oncology: Multifunctional Nano-Drug Delivery Systems for Synergistic Efficacy and Precision Modulation. [PDF]

Int J Nanomedicine
Gao T, Fu S, Quan X, Sun J, Jiang M, Li J.   +5 more
europepmc   +1 more source

Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value [PDF]

, 2015
Clare Stirzaker, Elena Zotenko, Susan J. Clark   +2 more
openalex   +1 more source

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

Anesthetic-induced epigenetic alterations: mechanisms and long-term clinical implications. [PDF]

Epigenetics
Shahidi Delshad E, Shamsi A, Mehrab Mohseni M, Abak N, Saberian M.   +4 more
europepmc   +1 more source

Roles of Histone Acetylation Modifiers and Other Epigenetic Regulators in Vascular Calcification

, 2020
Duk‐Hwa Kwon, Juhee Ryu, Young‐Kook Kim, Hyun Kook   +3 more
openalex   +1 more source

Epigenetics and pharmaco-epigenetics in the primary headaches [PDF]

The Journal of Headache and Pain, 2008
openaire   +2 more sources