Results 251 to 260 of about 849,922 (340)

EnsembleAge clock: a reliable and robust epigenetic age clock service reveals epigenetic age acceleration in opioid-overdosed brains. [PDF]

BMC Genomics
Anand A, Agarwal Y, Gupta T, Lin J, Ghemrawi M, Gerhard GS, Lee H.   +6 more
europepmc   +1 more source

Role of EZH2-mediated epigenetic modification on vascular smooth muscle in cardiovascular diseases: A mini-review [PDF]

Haiyan Luo, Yao Li, Honghu Song, Kui Zhao, Wenlin Li, Hailan Hong, Yunting Wang, Luming Qi, Yang Zhang   +8 more
openalex   +1 more source

Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective [PDF]

, 2018
Nivedita Chatterjee, Jiwan Gim, Jinhee Choi   +2 more
openalex   +1 more source

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

Beyond the genome: epigenetic regulation of immune responses and T cells in brain tumors. [PDF]

Front Immunol
Sun S, Han Y, Li H, Wang C, Zhou S, Zhang X, Dai S, Peng Y, Wang Z.   +8 more
europepmc   +1 more source

Activation of Latent HIV-1 T Cell Reservoirs with a Combination of Innate Immune and Epigenetic Regulators [PDF]

, 2019
Enrico Palermo, Chiara Acchioni, Daniele Di Carlo, Alessandra Zevini, Michela Muscolini, Matteo Ferrari, Luciano Castiello, Sara Virtuoso, Alessândra Borsetti, Guido Antonelli, Ombretta Turriziani, Marco Sgarbanti, John Hiscott   +12 more
openalex   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Exercise and Epigenetic Regulation in COPD: Current Evidence and Potential Mechanistic Pathways. [PDF]

Int J Mol Sci
Zhong Y, Xu J, Chen X, Lv Y, Zheng X.
europepmc   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Resistance of first-line targeted drugs in hepatocellular carcinoma: the epigenetic regulation mechanisms. [PDF]

Cell Death Dis
Qi D, Qin Y, Zhu H, Li Y, Han S.
europepmc   +1 more source