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Epigenetic regulation of HIV latency

Current Opinion in HIV and AIDS, 2011
A reservoir of latently infected cells remains in HIV-infected patients treated with highly active antiretroviral therapy treatment. Persistence of HIV in this latent reservoir has prevented full viral eradication. In order to understand and develop rational therapeutics to flush out HIV latency, the molecular mechanisms governing the phenomena of HIV ...
Shweta, Hakre   +3 more
openaire   +2 more sources

Epigenetic Regulation by Nuclear Receptors

Epigenomics, 2011
Nuclear receptors (NRs) represent a vital class of ligand-activated transcription factors responsible for coordinately regulating the expression of genes involved in numerous biological processes. Transcriptional regulation by NRs is conducted through interactions with multiple coactivator or corepressor complexes that modify the chromatin environment ...
Christopher D, Green, Jing-Dong J, Han
openaire   +2 more sources

Epigenetic Regulation of Autophagy

2019
Epigenetics refers to reversible and hereditary changes in gene expression without alterations in DNA sequences, such as DNA methylation, histone modification and chromatin remodelling. It was first proposed by Waddington in the book Introduction to Modern Genetics in 1939.
openaire   +2 more sources

Epigenetic regulation in ovarian cancer

Ovarian cancer is one of the diseases that have the highest mortality rate for women, especially women over 50 years old. In the future, incidence and mortality rates are predicted to extend in countries with low HDI. Instability in the structure and function of genetic factors has long been known as a cause of cancer, including ovarian cancer. Besides
Hue Vu, Thi, Anh-Dao, Ngo, Dinh-Toi, Chu
openaire   +2 more sources

MicroRNAs as Epigenetic Regulators of Obesity

In obesity, the process of adipogenesis largely determines the number of adipocytes in body fat depots. Adipogenesis is regulated by several adipocyte-selective micro-ribonucleic acids (miRNAs) and transcription factors that modulate adipocyte proliferation and differentiation.
Ayse Basak, Engin, Atilla, Engin
openaire   +2 more sources

Epigenetic Regulation in Breast Cancer: Insights on Epidrugs

Epigenomes, 2023
Woori Kwak, Hyunho Yoon
exaly  

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