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Epigenetic regulation in obesity
International Journal of Obesity, 2011The availability to the DNA strand and the activity of the transcription machinery is crucial for the cell to use the information in the DNA. The epigenetic mechanisms DNA methylation, modification of histone tails, other chromatin-modifying processes and interference by small RNAs regulate the cell-type-specific DNA expression. Epigenetic marks can be
C, Lavebratt, M, Almgren, T J, Ekström
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Epigenetic regulation of melanogenesis
Ageing Research Reviews, 2021Melanogenesis is a complex process in which melanin is synthesized in melanocytes and transported to keratinocytes, which involves multiple genes and signaling pathways. Epigenetics refers to the potential genetic changes that affect gene expression without involving changes in the original sequence of DNA nucleotides.
Shihang Zhou +12 more
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2015
Some of the key epigenetic regulatory mechanisms appeared early during evolution, and the acquisition of novel epigenetic regulators apparently facilitated certain evolutionary transitions. In this short review we focus mainly on the major epigenetic mechanisms that control chromatin structure and accessibility in mammalian cells.
Minárovits János +3 more
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Some of the key epigenetic regulatory mechanisms appeared early during evolution, and the acquisition of novel epigenetic regulators apparently facilitated certain evolutionary transitions. In this short review we focus mainly on the major epigenetic mechanisms that control chromatin structure and accessibility in mammalian cells.
Minárovits János +3 more
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Epigenetic regulation of flowering
Current Opinion in Plant Biology, 2007The acceleration of flowering by prolonged low temperature treatment (vernalization) has unique properties including the floral transition occurring at a time separate from the vernalization treatment. This implies the vernalization condition is inherited through mitotic divisions, but this vernalized state is not inherited from one generation to the ...
E S, Dennis, W J, Peacock
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Epigenetic Regulation in Drosophila
2006Epigenetic regulation of gene transcription relies on molecular marks like DNA methylation or histone modifications. Here we review recent advances in our understanding of epigenetic regulation in the fruit fly Drosophila melanogaster. In the past, DNA methylation research has primarily utilized mammalian model systems. However, several recent landmark
F, Lyko, C, Beisel, J, Marhold, R, Paro
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Epigenetic Regulation of Glycosylation
2021Expression of glycosylation-related genes (or glycogenes) is strictly regulated by transcription factors and epigenetic processes, both in normal and in pathological conditions. In fact, glycosylation is an essential mechanism through which proteins and lipids are modified to perform a variety of biological events, to adapt to environment, and to ...
Indellicato R., Trinchera M.
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Epigenetic regulation in obesity
Current Opinion in Clinical Nutrition and Metabolic Care, 2013Research suggests that 65% of variation in obesity is genetic. However, much of the known genetic associations have little known function and their effect size small, thus the gene-environment interaction, including epigenetic influences on gene expression, is suggested to be an important factor in the susceptibilty to obesity. This review will explore
Elaine M, Drummond, Eileen R, Gibney
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Epigenetic regulation of adipogenesis
Current Opinion in Clinical Nutrition and Metabolic Care, 2012Epigenetic regulation plays an essential role in cell differentiation, by allowing the establishment and maintenance of the gene-expression pattern of the mature cell type. Because of its importance in chronic diseases, adipogenesis is one of the best-studied differentiation processes.
Melina M, Musri, Marcelina, Párrizas
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Epigenetic Regulation in Psychiatric Disorders
Focus, 2007Many neurological and most psychiatric disorders are not due to mutations in a single gene; rather, they involve molecular disturbances entailing multiple genes and signals that control their expression. Recent research has demonstrated that complex 'epigenetic' mechanisms, which regulate gene activity without altering the DNA code, have long-lasting ...
Nadia, Tsankova +3 more
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PARP and Epigenetic Regulation
2008In the post-genome era attention is being focused on those epigenetic modifications which modulate chromatin structure to guarantee that information present on DNA is read correctly and at the most appropriate time in order to meet cellular requirements.
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