Results 131 to 140 of about 175,170 (271)

DNA and Human Language: Epigenetic Memory and Redundancy in Linear Sequence [PDF]

open access: yesarXiv
DNA is often described as the 'language of life', but whether it possesses formal linguistic properties remains unresolved. Here, we present the first empirical evidence that DNA sequences exhibit core linguistic features, specifically, functional and information redundancy, through comprehensive analysis of genomic and epigenetic datasets.
arxiv  

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II

open access: yesGenome Biology
Background How reversible glycosylation of DNA-bound proteins acts on transcription remains scarcely understood. O-linked β-N-acetylglucosamine (O-GlcNAc) is the only known form of glycosylation modifying nuclear proteins, including RNA polymerase II ...
Sofia Rucli   +6 more
doaj   +1 more source

Frequency‐Dependent Demethylation of Cancer DNAs by High‐Power Terahertz Radiation

open access: yesAdvanced Photonics Research, EarlyView.
Effective demethylation of cancer DNA is successfully demonstrated by resonant irradiation with high‐power terahertz (THz) waves at the 10 mW level, combined with metamaterial‐based THz filters. The dependence of spectral filtering on demethylation indicates that the resonant frequency of 1.6 THz of cancer DNAs plays a crucial role in reducing the ...
Chaeyoon Kim   +8 more
wiley   +1 more source

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

open access: yesAdvanced Science, EarlyView.
The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang   +20 more
wiley   +1 more source

Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration

open access: yesAdvanced Science, EarlyView.
This study reveals that Kdm6a plays key roles in repressing either peripheral nervous system (PNS) or central nervous system (CNS) axon regeneration, whereas Kdm6b is not involved in regulating CNS axon regeneration. Moreover, both demethylases are able to regulate CNS neuronal survival after injury, but with non‐overlapping mechanisms.
Shu‐Guang Yang   +13 more
wiley   +1 more source

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