Results 141 to 150 of about 189,865 (294)

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

Advanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad, Ahmad Amiri, Maik Böhmer, Soofia Khanahmadi   +3 more
wiley   +1 more source

Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites

, 2015
Alfonso Bellacosa, Alexander C. Drohat
openalex   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Reepithelialization of Diabetic Skin and Mucosal Wounds Is Rescued by Treatment With Epigenetic Inhibitors [PDF]

, 2023
Bo Yang, Stella Alimperti, Michael V. Gonzalez, Tzvete Dentchev, Minjung Kim, Justin Suh, Paul M. Titchenell, Kang I. Ko, John T. Seykora, Manju Benakanakere, Dana T. Graves   +10 more
openalex   +1 more source

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

Advanced Science, EarlyView.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang, Pengfei Jiang, Joshua B Stein, Yannan Hou, Chaochen Zhou, Heemin Kang, Ki‐Bum Lee   +6 more
wiley   +1 more source

Epigenetic Remodeling through Downregulation of Polycomb Repressive Complex 2 Mediates Chemotherapy Resistance in Testicular Germ Cell Tumors [PDF]

, 2019
Ratnakar Singh, Zeeshan Fazal, Andrea Corbet, Emmanuel Bikorimana, Jennifer Rodriguez, Ema M Khan, Khadeeja Shahid, Sarah J. Freemantle, Michael J. Spinella   +8 more
openalex   +1 more source

USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder [PDF]

, 2023
Julian Chéron, Leonardo Beccari, Perrine Hagué, Romain Icick, Chloé Despontin, Teresa Maria Carusone, Matthieu Defrance, Sagar Bhogaraju, Elena Martín‐García, Roberto Capellán, Rafaël Maldonado, Florence Vorspan, Jérôme Bonnefont, Alban de Kerchove d’Exaerde   +13 more
openalex   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

Advanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen, Ying Zhang, Zimeng Zhao, Yang Yang, Geng Guo, Yi Sun, Tao Zhang, Zhihong Zhang, Liqin Zeng, Wenxin Huang, Qingjun Shen, Ruining Han, Zhaohui He, Depeng Zhao, Huidong Zhang   +14 more
wiley   +1 more source

Genome-Wide Methylotyping Resolves Breast Cancer Epigenetic Heterogeneity and Suggests Novel Therapeutic Perspectives [PDF]

, 2019
А. С. Танас, В.О. Сигин, Alexey I. Kalinkin, Н. В. Литвяков, Е. М. Slonimskaya, М. К. Ибрагимова, E. Ignatova, О. А. Симонова, Ekaterina Kuznetsova, Т. В. Кекеева, Sergey S. Larin, Elena Poddubskaya, И. Д. Троценко, В. В. Руденко, Kristina Karandasheva, Kseniya Petrova, М. М. Цыганов, I. V. Deryusheva, П. В. Казанцева, А. В. Дорошенко, N. A. Tarabanovskaya, Galina G. Chesnokova, Marina Sekacheva, М. В. Немцова, Vera L. Izhevskaya, Sergey I. Kutsev, Zaletaev Dv, V. V. Strelnikov   +27 more
openalex   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source