Results 171 to 180 of about 175,170 (271)

Effects of Environmental Non-Essential Toxic Heavy Metals on Epigenetics During Development. [PDF]

Toxics
Kurita H, Ohuchi K, Inden M.
europepmc   +1 more source

Epigenetic control of an endogenous gene family is revealed by a novel blue fluorescent mutant of arabidopsis

, 1995
Judith Bender, Gerald R. Fink
openalex   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source

Epigenetics factors in schizophrenia: future directions for etiologic and therapeutic study approaches. [PDF]

Ann Gen Psychiatry
Yang H, Sun W, Li J, Zhang X.
europepmc   +1 more source

Cytosine Methylation Associated With Repeat-Induced Point Mutation Causes Epigenetic Gene Silencing in Neurospora crassa

, 1997
Jeffrey T. Irelan, Eric U. Selker
openalex   +2 more sources

Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers [PDF]

, 2000
Shannon A. Kuismanen, Mari Holmberg, Reijo Salovaara, Albert de la Chapelle, Païvi Peltomäki   +4 more
openalex   +1 more source

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

Advanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy, Bo Zhao, Ajda Lenardič, Huyen Thuc Tran Luong, Ori Bar‐Nur, Johan Auwerx, Martin Wohlwend   +6 more
wiley   +1 more source

Epigenetics as the molecular substrate of multimodal lifestyle approaches for patients with persistent pain. [PDF]

Braz J Phys Ther
Polli A, Nijs J, Thienpont B.
europepmc   +1 more source

Nickel carcinogenesis, mutation, epigenetics, or selection.

, 1999
Max Costa, Catherine B. Klein
openalex   +1 more source

CK2B Induces CD8+ T‐Cell Exhaustion through HDAC8‐Mediated Epigenetic Reprogramming to Limit the Efficacy of Anti‐PD‐1 Therapy in Non‐Small‐Cell Lung Cancer

Advanced Science, EarlyView.
αPD‐1 therapy has left an indelible mark in the field of NSCLC treatment; however, its efficacy is limited in clinical practice owing to the effector T‐cell exhaustion. These findings underscore CK2B as a promising target for overcoming the exhaustion of effector CD8+ T cells, thereby enhancing the efficacy of αPD‐1 and adoptive cell therapies in NSCLC.
Shaochuan Liu, Shiya Ma, Gen Liu, Lingjie Hou, Yong Guan, Liang Liu, Yuan Meng, Wenwen Yu, Ting Liu, Li Zhou, Zhiyong Yuan, Shuju Pang, Siyuan Zhang, Junyi Li, Xiubao Ren, Qian Sun   +15 more
wiley   +1 more source