Results 171 to 180 of about 369,301 (351)
GENETIC AND EPIGENETIC CONTROL OF SEVERAL ISOZYMIC SYSTEMS IN TETRAHYMENA * [PDF]
, 1968 Sally Lyman Allen
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Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance [PDF]
, 1997 Z. Jeffrey Chen, Craig S. Pikaard
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Advanced Healthcare Materials, EarlyView.This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah +9 more
wiley +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
Advanced Materials, EarlyView.DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
The pathogenesis of Tourette's syndrome: Epigenetic factors active in early CNS development
, 1993 James F. Leckman, Bradley S. Peterson
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An upstream activator of transcription coordinately increases the level and epigenetic stability of gene expression [PDF]
, 1996 Wendy Magis +3 more
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Advanced Materials, EarlyView.This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang +22 more
wiley +1 more source
Epigenetics: Novel Therapeutics Targeting Epigenetics
Journal of Medicinal Chemistry, 2014 Stuart J. Conway +6 more
openaire +5 more sources