Results 171 to 180 of about 458,162 (417)
Evidence of epigenetic oncogenesis: a turning point in cancer research [PDF]
In cancer research, the term epigenetics was used in the 1970s in its modern sense encompassing non-genetic events modifying the chromatin state, mainly to oppose the emerging oncogene paradigm. However, starting from the establishment of this prominent concept, the importance of these epigenetic phenomena in cancer rarely led to questioning the causal
arxiv +1 more source
Epigenetic common opal from the Hawkesbury Sandstone Formation of the Sydney Basin [PDF]
, 1952 J. F. Lovering
openalex +1 more source
Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment
Nature CommunicationsImmune cells must adapt to different environments during the course of an immune response. Here we study the adaptation of CD8+ T cells to the intestinal microenvironment and how this process shapes the establishment of the CD8+ T cell pool. CD8+ T cells
Matteo Villa +26 more
doaj +1 more source
Nature Communications, 2019 XACT is a primate-specific TE-derived lncRNA that coats active X chromosomes in pluripotent cells and may contribute to species-specific regulation of X chromosome inactivation.
Miguel Casanova +7 more
doaj +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
A Genetic Programming System with an Epigenetic Mechanism for Traffic Signal Control [PDF]
arXiv, 2019 Traffic congestion is an increasing problem in most cities around the world. It impacts businesses as well as commuters, small cities and large ones in developing as well as developed economies. One approach to decrease urban traffic congestion is to optimize the traffic signal behaviour in order to be adaptive to changes in the traffic conditions ...
arxiv
Epigenetics in cancer stem cells
Molecular Cancer, 2017 Compelling evidence have demonstrated that bulk tumors can arise from a unique subset of cells commonly termed “cancer stem cells” that has been proposed to be a strong driving force of tumorigenesis and a key mechanism of therapeutic resistance.
T. Toh, J. Lim, E. Chow
semanticscholar +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Epigenetic mineralization and areas favorable for uranium exploration in Tertiary continental sedimentary rock in south-central Alaska: A preliminary report [PDF]
, 1978 Kendell A. Dickinson, John Campbell
openalex +1 more source