Results 221 to 230 of about 369,301 (351)

Advances in pancreatic cancer epigenetics: From the mechanism to the clinic. [PDF]

World J Gastrointest Oncol
Zhou JD, Shen HZ.
europepmc   +1 more source

Genetic and Epigenetic Modification of MLH1 [PDF]

, 2000
Manuel Perucho, Shannon A. Kuismanen, Mari Holmberg, Reijo Salovaara   +3 more
openalex   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Insulin levels at 18-20 gestational weeks in pregnant women with obesity are associated with newborn abdominal fat deposition and DNA methylation in cord blood. [PDF]

Clin Epigenetics
Maguolo A, Jönsson J, Perfilyev A, Vaag A, Malchau Carlsen E, Nørgaard K, Franks PW, Renault KM, Ling C.   +8 more
europepmc   +1 more source

Epigenetic control of an endogenous gene family is revealed by a novel blue fluorescent mutant of arabidopsis

, 1995
Judith Bender, Gerald R. Fink
openalex   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Strengthening Rigor and Reproducibility in Epigenome-Wide Association Studies of Social Exposures and Brain-Based Health Outcomes. [PDF]

Curr Environ Health Rep
McKenna BG, Lussier AA, Suderman MJ, Walton E, Simpkin AJ, Hüls A, Dunn EC.   +6 more
europepmc   +1 more source

Nickel carcinogenesis, mutation, epigenetics, or selection.

, 1999
Max Costa, Catherine B. Klein
openalex   +1 more source

Biallelic Inactivation of Retinoic Acid Receptor β2 Gene by Epigenetic Change in Breast Cancer [PDF]

, 2001
Qifeng Yang, Ichiro Mori, Liang Shan, Misa Nakamura, Yasushi Nakamura, Hirotoshi Utsunomiya, Goro Yoshimura, Takaomi Suzuma, Takeshi Tamaki, Teiji Umemura, Takeo Sakurai, Kennichi Kakudo   +11 more
openalex   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source