Results 261 to 270 of about 369,301 (351)

Epigenetic age acceleration and allergic diseases: a bidirectional two-sample Mendelian randomization study. [PDF]

Clin Epigenetics
Sun J, Fan G, Hu L, Qu ZH, Jiang H.
europepmc   +1 more source

An Antagonism Between Ethylene Signaling and DNA Methylation Orchestrates the Progression of Leaf Senescence in Non‐heading Chinese Cabbage

Advanced Science, EarlyView.
CMT2 mediates the maintenance of DNA methylation on the promoters of SAGs, thereby inhibiting EIN3A untimely activating SAGs’ expression. Aging‐impelled striking upregulation of EIN3A strongly suppresses the expression of CMT2 to reduce the methylation level, which releases the activation of EIN3A on SAGs, thus initiating and accelerating the ...
Dingyu Zhang, Yong Luo, Han Wang, Xiaofeng Li, Liming Miao, Lu Gao, Haibo Hao, Xinman Wang, Benke Kuai, Hongfang Zhu, Guodong Ren   +10 more
wiley   +1 more source

RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications. [PDF]

MedComm (2020)
Huang S, Li Z, Lin W, Xie R, Huang H.
europepmc   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Epigenetic factors associated with peri-implantitis: a review. [PDF]

J Zhejiang Univ Sci B
Li Q, Lu H, Zhang M, Ye Y, Chen Q, Sun P.   +5 more
europepmc   +1 more source

CircTP53/USP10/p53 signaling Axis as a Novel Regulator of Progression and Prognosis of Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang, Fen Chang, Zinan Li, Chengcheng Duan, Xiangkai Sun, Siyu Wang, Dongmin Wei, Wenming Li, Ye Qian, Shengda Cao, Juan Zhao, Dapeng Lei   +11 more
wiley   +1 more source

Correction: Respiratory infection‑ and asthma‑prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways. [PDF]

Clin Epigenetics
Martino D, Schultz N, Kaur R, van Haren SD, Kresoje N, Hoch A, Diray-Arce J, Su JL, Levy O, Pichichero M, in association with the IDEAL Consortium.   +10 more
europepmc   +1 more source

Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly

, 2001
Jun‐ichi Nakayama, Judd C. Rice, Brian D. Strahl, C. David Allis, Shiv I. S. Grewal   +4 more
openalex   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Changes of methylation at enhancers appear to be essential for HIV infection progression. [PDF]

Clin Epigenetics
Taryma-Leśniak O, Bińkowski J, Mielczak K, Aksak-Wąs B, Karasińska-Cieślak M, Sobalska-Kwapis M, Strapagiel D, Parczewski M, Wojdacz TK.   +8 more
europepmc   +1 more source