Results 321 to 330 of about 475,691 (380)

Retraction Note to: A novel miRNA identified in GRSF1 complex drives the metastasis via the PIK3R3/AKT/NF-κB and TIMP3/MMP9 pathways in cervical cancer cells. [PDF]

Cell Death Dis
Sun Q, Yang Z, Li P, Wang X, Sun L, Wang S, Liu M, Tang H.   +7 more
europepmc   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

Epigenetics Through Generations and Across Phylogenies: An Interview with Dr. Bluma Lesch. [PDF]

Yale J Biol Med
Abu-Shamma R, Marijic Buljubasic A.
europepmc   +1 more source

C ^m C(a/t)GG methylation: A new epigenetic mark in mammalian DNA?

, 2001
Matthew C. Lorincz, Mark Groudine
openalex   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

Advanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang, Donglan Tang, Chenxi Yang, Chao Lin, Yingyue Yuan, Meiying He, Yiying Chen, Zhuo Mao, Ying Ying, Xiaosong Ma, Xiangchen Kong   +10 more
wiley   +1 more source

Deciphering the Molecular Dialogue: Mitochondria, Epigenetics, and Extracellular Vesicles in Placental Function and Pregnancy Complications. [PDF]

Compr Physiol
Lien YC, Simmons RA.
europepmc   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen, Mengqin Shen, Haitao Zhao, Liu Liu, Qian Hua, Xiaoping Zhao, Jianjun Liu, Haizhong Feng, Gang Huang   +8 more
wiley   +1 more source

Exploring the Link Between the Gut Microbiota and Epigenetic Factors in Anorexia Nervosa. [PDF]

Brain Behav
Korten NM, Thelen AC, Voelz C, Beyer C, Seitz J, Trinh S, Blischke L.   +6 more
europepmc   +1 more source

Finding your way through the science maze

, 2018
Akhtar, A.
core   +1 more source