Results 31 to 40 of about 99,774 (210)

Monoterapia con los nuevos anticonvulsivantes

Acta Neurológica Colombiana, 2006
Los nuevos antiepilépticos tienen ventajas potenciales como diferentes mecanismos de acción, menos interacciones medicamentosas, mejor rango terapéutico, menos efectos secundarios, mejor farmacocinética y en la mayoría no hay necesidad de monitoria de ...
Ignacio Valencia
doaj   +2 more sources

Exploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1

Epileptic Disorders, EarlyView.
Abstract Objective Progressive myoclonic epilepsy type 1 (EPM1) is a neurodegenerative disease caused by biallelic variants in the cystatin B (CSTB) gene. Despite a progressive course, phenotype severity varies among patients, even within families. We studied the potential role of APOE ε4 in modifying phenotypic diversity in EPM1, given its established
Janina Gunnar, Yawu Liu, Henri Eronen, Tarja Joensuu, Marja Äikiä, Jelena Hyppönen, Katri Silvennoinen, Esa Mervaala, Juhana Hakumäki, Anna‐Elina Lehesjoki, Reetta Kälviäinen   +10 more
wiley   +1 more source

Effect of oxidative stress on ABC transporters: contribution to epilepsy pharmacoresistance [PDF]

, 2017
Epilepsy is a neurological disorder affecting around 1%-2% of population worldwide and its treatment includes use of antiepileptic drugs to control seizures. Failure to respond to antiepileptic drug therapy is a major clinical problem and over expression
Grewal, G. K., Kanojia, N., Kukal, S., Kukreti, R., Kukreti, S., Saso, L.   +5 more
core   +2 more sources

Resolution of generalized tonic seizures following focal ablative or resective surgery

Epileptic Disorders, EarlyView.
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman, Itay Tokatly Latzer, Aaron E. L. Warren, Jurriaan M. Peters   +3 more
wiley   +1 more source

Crisis de pánico, un reto diagnóstico

Acta Neurológica Colombiana, 2023
Las manifestaciones de pánico asociadas a la epilepsia del lóbulo temporal pueden ser difíciles de diferenciar de los ataques de pánico que hacen parte de los trastornos de ansiedad.
Martin Torres Z, Esther V. Perea C, Irma Caro C., Luis Polo V.   +3 more
doaj   +2 more sources

Measures of Health-Related Quality of Life Outcomes in Pediatric Neurosurgery: Literature Review [PDF]

, 2019
Background Improving value in healthcare means optimizing outcomes and minimizing costs. The emerging pay-for-performance era requires understanding of the effect of healthcare services on health-related quality of life (HRQoL).
Desai, Virendra R., Gadgil, Nisha, Lam, Sandi K., Raskin, Jeffrey S., Saad, Shahbaz   +4 more
core   +1 more source

Preclinical signal for a disease‐modifying effect on seizure cluster severity with intermittent diazepam treatment

Epilepsia, EarlyView.
Abstract Objective In epilepsy, daily treatment provides only symptomatic seizure control, leaving a significant unmet need for a treatment that affects the underlying predisposition to seizures. Here, in a first‐of‐its‐kind study, we test the hypothesis that intermittent treatment of seizure clusters with diazepam in the kainic acid post‐status ...
Qian Wu, Michelle Guignet, Jonathan Vuong, H. Steve White, Wesley T. Kerr, Evelyn K. Shih, Leock Y. Ngo, Enrique Carrazana, Adrian L. Rabinowicz   +8 more
wiley   +1 more source

¿Qué aportan los nuevos fármacos antiepilépticos?

Revista Médica Clínica Las Condes, 2013
Casi 40% de los pacientes con epilepsia no responde a nuestra primera elección de fármacos antiepilépticos, (FAEs). Esto debería ser justificación suficiente para la búsqueda de nuevos compuestos.
Dr. Parra Jaime
doaj   +1 more source

A call for ethical, equitable, and effective artificial intelligence to improve care for all people with epilepsy: A roadmap. A report by the ILAE Global Advocacy Council and Big Data Commission

Epilepsia, EarlyView.
Abstract The artificial intelligence (AI) revolution is upon us. It will inevitably form a central component of epilepsy workflows and patient advocacy. Therefore, it behooves us as health care providers to ride the crest of this wave and guide its direction for the benefit of all people with epilepsy.
Colin B. Josephson, Sandor Beniczky, Spiros Denaxas, Akio Ikeda, Lara Jehi, Angelina Kakooza Mwesige, Nathalie Jette, Gabriel Davis Jones, Philippe Ryvlin, Arjune Sen, Chahnez Charfi Triki, Gabriella Waters, Alla Guekht, J. Helen Cross   +13 more
wiley   +1 more source

Quantifying the impact of a computer‐aided diagnostic score on the clinical diagnosis of functional seizures

Epilepsia, EarlyView.
Abstract Objective The diagnosis of functional/dissociative seizures (FDS) without ictal video‐electroencephalography is challenging. The Functional/Dissociative Seizures Likelihood Score (FSLS) is a machine learning‐based diagnostic score that aims to help clinicians identify FDS.
Wesley T. Kerr, Katherine N. McFarlane, Corinne H. Allas, Samuel W. Terman, Markus Reuber, Sung Hyun Seo, Payge Barnard, Adriana Y. Koek, Amir H. Karimi, Siddhika S. Sreenivasan, Jena S. Grauer, Di Sun, Meagan Watson, Elissa H. Patterson, James Castellano, Anto I. Bagić, L. Brian Hickman, Kenneth H. Kutschman, Laurence Knowles, Alistair Wardrope, Piyush Ostwal, Bridget K. MacDonald, Melissa Berry, Lomalan Reddy, Najda Robinson‐Mayer, Nicholas J. Beimer, Rachna Reddy, Sarah K. Yaghoubi, Laura A. Kirkpatrick, Danielle R. Carns, Alex J. Israel, Jamie D. Feusner, Zongqi Xia, Yanshan Wang, Laura A. Strom, Page B. Pennell, John M. Stern, Lubomir Hadjiiski, William C. Stacey   +38 more
wiley   +1 more source