Results 31 to 40 of about 11,514 (169)
Freedon study: Real‐life outcomes of cenobamate in different lines of treatment
Epilepsia, EarlyView.Abstract Objectives Cenobamate is an antiseizure medication (ASM) with proven effectiveness in individuals with highly refractory epilepsy. This study investigated the effectiveness and tolerability of cenobamate in different treatment lines and a less refractory setting. Methods This was a multicenter, retrospective, observational study.
Vicente Villanueva +50 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Discussing sudden unexpected death in epilepsy (SUDEP) is difficult and sensitive for health care providers (HCPs), people with epilepsy (PwE), and caregivers. This scoping review examines the literature on SUDEP communication, focusing on need, timing, content, methods, facilitators, barriers, and outcomes. We performed a thematic analysis to
Amir Aschner +5 more
wiley +1 more source
Neurología (English Edition), 2013 Introduction: Reports on surgical outcomes in patients with drug-resistant temporal lobe epilepsy without histological abnormalities are scarce. Methods: Retrospective review of data from patients with drug-resistant temporal lobe epilepsy and no ...
J.C. Benedetti-Isaac +6 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin +7 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective This study was undertaken to present the results of an exploratory phase 2 trial of stiripentol in Lennox–Gastaut syndrome (LGS). Methods This exploratory single‐blind, single‐arm, nonrandomized sequential‐period phase 2 study was conducted at four centers in France between January 1989 and August 1993.
Stéphane Auvin +3 more
wiley +1 more source
Revista Médica Clínica Las Condes, 2013 Hay muchos aspectos por abordar en el manejo de las mujeres con epilepsia, relacionados con su rol en la reproducción. Algunos de éstos necesitan ser considerados en la adolescencia, otros están relacionados con el embarazo, afectando tanto a la madre ...
S. Andrea Contreras, Dra. +1 more
doaj +1 more source
Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome
Epilepsia, EarlyView.Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan +14 more
wiley +1 more source
Neurología, 2013 Resumen: Introducción: Los reportes de los resultados quirúrgicos en los pacientes con epilepsia fármaco-resistente del lóbulo temporal sin anormalidades histológicas son escasos.
J.C. Benedetti-Isaac +6 more
doaj +1 more source
Defining the end point of status epilepticus: A scoping review and framework for standardization
Epilepsia, EarlyView.Abstract Status epilepticus (SE) is a life‐threatening neurological emergency with consensus‐driven definitions for onset but no standardized criteria for its end point. This gap creates uncertainty in research and clinical practice. We conducted a scoping review to evaluate how end points have been defined in SE research and to identify key areas of ...
Fawad A. Khan +6 more
wiley +1 more source
Neurología, 2015 Resumen: Introducción: La epilepsia es uno de los trastornos neurológicos más frecuentes de la infancia, presentándose en un 0,5-1%. Aproximadamente un 20-30% de los pacientes son farmacorresistentes.
A. Ulate-Campos +10 more
doaj +1 more source