Results 171 to 180 of about 6,465 (257)

Assessing the diagnostic performance of investigations in pediatric myoclonic epilepsies: A retrospective cohort study. [PDF]

Epilepsia
Brulé S, Dozières-Puyravel B, Nasser H, Elmaleh-Bergès M, Mauvais FX, Auvin S.   +5 more
europepmc   +1 more source

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

Epilepsia Open, Volume 11, Issue 4, Page 1200-1213, August 2026.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi, Ezio Calò, Maria Teresa Di Claudio, Carmela Pia Ferro, Umberto Costantino, Elio Perrone, Raffaela Rita Latino   +6 more
wiley   +1 more source

Vagus nerve stimulation in <i>KCNB1</i>-related developmental and epileptic encephalopathy: A case of seizure reduction and review of literature. [PDF]

Epilepsy Behav Rep
Sayanagi T, Kosugi K, Ogawa E, Takenouchi T, Yamada M, Kosaki K, Sugiyama I, Toda M.   +7 more
europepmc   +1 more source

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

Epilepsia Open, Volume 11, Issue 4, Page 1214-1226, August 2026.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston, Justine Curley, Ryan Verner, Maxine Dibue, Charles Gordon, Gaia Giannicola, Kathryn Nichol   +6 more
wiley   +1 more source

Early-Onset and Syndromic Pediatric Epilepsy in Kazakhstan: Clinical, Molecular, and Phenotypic Spectrum. [PDF]

J Clin Med
Bayanova M, Nazarova L, Zhakupov A, Malik D, Gabdulkayum A, Mirmanova Z, Satvaldina N, Rakhimova S, Akilzhanova A, Yerezhepov D, Bolatov A.   +10 more
europepmc   +1 more source

Real‐world outcomes of responsive neurostimulation in patients with Lennox–Gastaut syndrome: A multicenter retrospective study

Epilepsia Open, Volume 11, Issue 4, Page 1244-1254, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple seizure types and high resistance to antiseizure medication (ASM), often necessitating nonpharmacologic therapies, including neuromodulation.
Shanna M. Swartwood, Robert J. Bollo, Catherine J. Chu, Alexandra L. Geffrey, Robert Mark Richardson, Hiroki Nariai, Aria Fallah, Samuel Ahn, Saadi Ghatan, Laura Chenevert, Maite La Vega‐Talbott, Audie C. Espinoza   +11 more
wiley   +1 more source

A practical guide to the updated seizure classification 2025. [PDF]

Epileptic Disord
Beniczky S, Trinka E, Wirrell E, Singh MB, Blumenfeld H, Bogacz Fressola A, Cendes F, Craiu D, Frauscher B, Jansen FE, Kahane P, Kander V, Kishk N, Khoo CS, Lizcano A, De Palma L, Ryvlin P, Specchio N, Sperling MR, Tatum W, Yacubian EM, Wilmshurst J, Cross JH.   +22 more
europepmc   +1 more source

Occurrence and clinical correlates of depressive symptoms in adults with epilepsy: A study in Georgia

Epilepsia Open, Volume 11, Issue 4, Page 1290-1300, August 2026.
Abstract Objective To evaluate the occurrence, clinical correlates, and screening accuracy of depressive symptoms (DS) among adults with epilepsy in Georgia, a country with limited mental health resources. Methods We conducted a cross‐sectional study in adults with epilepsy attending a tertiary care center. We assessed DS using two validated tools: the
Ketevan Silagadze, Eka Burkadze, Maka Areshidze, Teimuraz Silagadze, Sofia Kasradze, Josemir W. Sander   +5 more
wiley   +1 more source

AFG2A-related encephalopathy, expanding the neurodevelopmental and epileptic spectrum. [PDF]

Orphanet J Rare Dis
Nou-Fontanet L, Cantalupo G, Braun F, Camacho AR, Álvarez VG, Chilavert VD, Insuga VS, Fernández LA, Alonso-Colmenero I, Arzimanoglou A, Fons C.   +10 more
europepmc   +1 more source

Smartphone videos for infantile epileptic spasms triaging and assessment (VISTA study): Impact of education and standardized clinical history on diagnostic accuracy

Epilepsia Open, Volume 11, Issue 4, Page 1301-1313, August 2026.
Abstract Objective Diagnostic and treatment delays in infantile epileptic spasms syndrome (IESS) increase the risk of poor neurodevelopmental outcomes. Early clinical recognition of IESS is essential, especially in regions lacking expedited access to electroencephalograms (EEG).
Christine L. Shrock, Margaret C. Savage, Lauren Sham, Christopher Cortina, Kathryn P. Gray, I‐Hsiu Lee, Chahnez C. Triki, Jacqueline French, J. Helen Cross, Orrin Devinsky, Jo M. Wilmshurst, Archana A. Patel   +11 more
wiley   +1 more source