Results 21 to 30 of about 1,388,000 (303)

Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs

Health Technology Assessment, 2021
Background: Levetiracetam (Keppra®, UCB Pharma Ltd, Slough, UK) and zonisamide (Zonegran®, Eisai Co. Ltd, Tokyo, Japan) are licensed as monotherapy for focal epilepsy, and levetiracetam is increasingly used as a first-line treatment for generalised ...
Anthony G Marson, Girvan Burnside, Richard Appleton, Dave Smith, John Paul Leach, Graeme Sills, Catrin Tudur-Smith, Catrin O Plumpton, Dyfrig A Hughes, Paula R Williamson, Gus Baker, Silviya Balabanova, Claire Taylor, Richard Brown, Dan Hindley, Stephen Howell, Melissa Maguire, Rajiv Mohanraj, Philip EM Smith   +18 more
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EEG–fMRI of idiopathic and secondarily generalized epilepsies [PDF]

, 2006
We used simultaneous EEG and functional MRI (EEG–fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE).
Lemieux, L., Hamandi, Khalid, Friston, K., Salek-Haddadi, Afraim, Laufs, Helmut, Friston, Karl, Lemieux, Louis, Duncan, John S., Liston, Adam, Duncan, J.S., Hamandi, K., Laufs, H., Fish, David R., Liston, A., Salek-Haddadi, A., Fish, D.R.   +15 more
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Familial partial epilepsies [PDF]

, 2014
OBJECTIVE: To investigate the clinical and genetic characteristics of familial partial epilepsies. METHOD: Family history of seizures was questioned in all patients followed in our epilepsy clinics, from October 1997 to December 1998. Those with positive
Guerreiro, M M, Scotoni, A E, Sousa, S C, Carvalho, M I, LOPES-CENDES, ISCIA, CARVALHO, MARIA IMACULADA, Lopes-Cendes, I, SOUSA, SOLANGE C., GUERREIRO, CARLOS A.M., CENDES, FERNANDO, GUERREIRO, MARILISA M., Guerreiro, C A, SCOTONI, ANNA E., Kobayashi, E, Cendes, F, KOBAYASHI, ELIANE   +15 more
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Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. [PDF]

, 2010
Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully revealed common variants associated with disease
Jamnadas-Khoda, J, Dena G. Hernandez, Sarah K. Tate, Michael R. Johnson, Doherty, Colin P, Gibson, Rachel A, John S. Duncan, Johnson, Michael R, Saud Alhusaini, Husain, A M, Radtke, R A, Cavalleri, Gianpiero L, Chinthapalli, Krishna, Tate, Sarah K, Wieser, H G, Hosford, D, Massimo Pandolfo, Hernandez, D G, Kramer, G, Tate, S K, Shianna, K V, Steinhoff, B J, Norman Delanty, Jamnadas-Khoda, Jenny, David Hosford, Alhusaini, Saud, Steinhoff, Bernhard J, Doherty, C P, Duncan, J S, Chantal Depondt, Lefkos T. Middleton, Erin L. Heinzen, Depondt, C, Dominik Zumsteg, Duncan, John S, David Leppert, Bernhard J. Steinhoff, Pandolfo, Massimo, Wood, Nicholas W, Mikati, M A, Paul M. Matthews, Jörg Hansen, Delanty, N, Hansen, J, Mohamad A. Mikati, Heuser, Kjell, Pandolfo, M, Wieser, Heinz-Gregor, Goldstein, D B, Luis O. Caboclo, Gjerstad, L, Sisodiya, S M, Catarino, Claudia B, Kai J. Eriksson, Heinzen, Erin, Matthews, Paul M, Anne-Mari Kantanen, Kasperavičiūtė, Dalia, Caboclo, L O, Thomas Dorn, Heinzen, Erin L, Zumsteg, Dominik, Sander, J W, Mikati, Mohamad A, Jenny Jamnadas-Khoda, Delanty, Norman, Shianna, Kevin V, Heinzen, E L, Eriksson, Kai J, Rachel A. Gibson, David B. Goldstein, Sanjay M. Sisodiya, Middleton, Lefkos T, Hernandez, Dena G, Peuralinna, T, Leslie Amos, Reetta K. Kälviäinen, Clayton, Lisa MS, Dorn, Thomas, Aatif M. Husain, Kantanen, Anne-Mari, Gallentine, W B, Kraermer, Guernter, Nicholas W. Wood, Hansen, Joerg, Colin P. Doherty, Gibson, R A, Leif Gjerstad, Sisodiya, Sanjay M, Kevin V. Shianna, Kasperaviciūte, D, Peuralinna, Terhi, Hansen, Jörg, Dalia Kasperavičiūtė, Radtke, Rodney A, Husain, Aatif M, Terhi Peuralinna, Josemir W. Sander, Wood, N W, Gallentine, William B, Heuser, K, Leppert, D, Lisa M.S. Clayton, Eriksson, Kai, Eriksson, K J, Kalviainen, Reetta, Claudia B. Catarino, Clayton, Lisa M S, Johnson, M R, Heinz-Gregor Wieser, Kalviainen, Reetta K, Gianpiero L. Cavalleri, Goldstein, David B, Dorn, T, Leppert, David, Cavalleri, G L, Marcos Ortega, Catarino, C B, Kälviäinen, R K, Kantanen, A M, Depondt, Chantal, Clayton, L M S, Rodney A. Radtke, Matthews, P M, Ortega, Marcos, Alhusaini, S, Ortega, M, Hosford, David, Zumsteg, D, Chinthapalli, K, Amos, L, Günter Krämer, Gjerstad, Leif, Amos, Leslie, Krishna Chinthapalli, William B. Gallentine, Middleton, L T, Caboclo, Luis O, Kjell Heuser, Sander, Josemir W   +139 more
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Association mapping of genomic microdeletions and common susceptibility variants predisposing to genetic generalized epilepsies [PDF]

, 2013
Approximately 3% of the general population is affected by epilepsy during lifetime, making epilepsy one of the most common neurological diseases. Genetic generalized epilepsies (GGE) are the most common of genetic epilepsies and account for 20-30% of ...
Trucks, Holger Sebastian
core   +1 more source

Identifying SNP targeted pathways in partial epilepsies with genome-wide association study data

, 2021
Purpose: In a recent genome-wide association study for partial epilepsies in the European population, a common genetic variation has been reported to affect partial epilepsy only modestly.
Iseri, S. Ugur, Sezerman, O. U., Bakir-Gungor, B., Tuncer, F. N., Baykan, BETÜL   +4 more
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Localizing Value of Clinical Seizure Patterns

Pediatric Neurology Briefs, 1996
The value of ictal clinical manifestations in differentiating frontal and temporal lobe partial epilepsies was determined in a prospective study of 252 patients selected according to imaging, EEG, and focal clinical patterns from records at the National ...
J Gordon Millichap
doaj   +1 more source

Improved diagnosis in children with partial epilepsy using a multivariable prediction model based on EEG network characteristics. [PDF]

PLoS ONE, 2013
BACKGROUND: Electroencephalogram (EEG) acquisition is routinely performed to support an epileptic origin of paroxysmal events in patients referred with a possible diagnosis of epilepsy. However, in children with partial epilepsies the interictal EEGs are
Eric van Diessen, Willem M Otte, Kees P J Braun, Cornelis J Stam, Floor E Jansen   +4 more
doaj   +1 more source

Nocturnal epilepsies in adults [PDF]

, 1997
We evaluated the clinical characteristics and the electroencephalographic (EEG) findings by long video-EEG monitoring in 64 successive patients with definite nocturnal seizures. Mental state, neurological examination, neuroimaging and EEG background were
Yaqub, Basim A, Waheed, Ghazala, Kabiraj, Mohammad Mu   +2 more
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Frequency and Stratification of Epileptogenic Lesions in Elderly With New Onset Seizures

Frontiers in Neurology, 2018
Objective: To evaluate prospectively the frequency of epileptogenic lesions in a consecutive cohort of elderly patients presenting with new onset unprovoked seizures, and who underwent a complete evaluation including dedicated epilepsy protocol MRI ...
Maher Arabi, Maya Dirani, Roula Hourani, Wassim Nasreddine, Jaafar Wazne, Samir Atweh, Heba Samara, Abdel Rahman Shatila, Ahmad Beydoun   +8 more
doaj   +1 more source