A study on interictal depressive symptoms and laterality in temporal lobe and generalized epilepsies
Annals of Indian Psychiatry, 2017 Background: Mood disorders like inter-ictal depressive symptoms and inter-ictal major depressive episodes are the most frequent psychiatric co-morbidity seen in temporal lobe epilepsies with left hippocampal sclerosis than generalized epilepsies. Despite
Neena S Sawant, Biswarup M Ghosh
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Transient lesion in the splenium of the corpus callosum and a sudden antiepileptic drugs withdrawal: A case with focal epilepsy in presurgical evaluation [PDF]
Vojnosanitetski Pregled, 2010 Introduction. A sudden withdrawal of antiepileptic drugs gives higher rate of epileptic seizures in the settings of video electroencephalography (vEEG), monitoring that is a subject to further registration and analysis.
Ristić Aleksandar +7 more
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PET Scanning in Partial Epilepsy [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1991 ABSTRACT:Many biologically active tracers are available for positron emission tomography (PET) investigations, but most studies of epilepsy have utilized l8F-fluorodeoxyglucose (FDG) to measure local cerebral metabolic rate for glucose. Over 70% of patients with medically refractory partial seizures demonstrate an interictal zone of hypometabolism ...
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Association mapping of genomic microdeletions and common susceptibility variants predisposing to genetic generalized epilepsies [PDF]
, 2013 Approximately 3% of the general population is affected by epilepsy during lifetime, making epilepsy one of the most common neurological diseases. Genetic generalized epilepsies (GGE) are the most common of genetic epilepsies and account for 20-30% of ...
Trucks, Holger Sebastian
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Cessation of еpileptic seizures series using peroral valproate in an adult patient with partial epilepsy [PDF]
Vojnosanitetski Pregled, 2007 Introduction. Golden rule for the initiation of antiepileptic therapy in the majority of epileptic syndromes is "start low and go slow", a principle after the second unprovoked seizure. There are certain clinical situations however when fast titration of
Spasić Mirjana, Lukić Stevo
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Current clinical evidence on topiramate pharmacokinetics [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 Topiramate is biochemically classified as a fructopyranose sulphamate. Discovered as early as 1979, during middle 1980's it was approved in many countries for the treatment of epilepsies and migraine prevention.
Jakovljević Mihajlo +4 more
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
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FEBS Letters, EarlyView.Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
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Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study [PDF]
, 2017 Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully revealed common variants associated with disease
Pandolfo, Massimo +44 more
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