Results 91 to 100 of about 33,305 (301)
Biological Basis of Primary Generalized Epilepsies—Genetics
, 2017 Primary generalized epilepsies account for 30% of all epilepsies. These age-related epilepsies without structural brain lesions and normal development have a high heritability. Based on the main seizure type and their age of onset, four main subsyndromes
Carla Marini, Renzo Guerrini
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Benign rolandic and occipital epilepsies of childhood
, 2012 Rolandic and occipital benign epilepsies of childhood are strictly linked to sleep but often no specific alterations of sleep organization were found. The spike activation is mostly evident in the first sleep cycle and related to EEG sigma band.
della Corte, M. +11 more
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Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Epileptic neuronal networks: methods of identification andclinical relevance.
Frontiers in Neurology, 2013 The main objective of this paper is to examine evidence for the concept that epileptic activityshould be envisaged in terms of functional connectivity and dynamics of neuronal networks,Basic concepts regarding structure and dynamics of neuronal networks ...
Hermann eStefan +1 more
doaj +1 more source
Reflex epilepsies: a review [PDF]
, 2008 Reflex seizures are evoked by a specific afferent stimulus or by activity of the patient and are divided into those characterized by generalized seizures and those principally manifested by focal seizures.
Karaman, Handan Ozisik +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
The system epilepsies: a pathophysiological hypothesis.
, 2012 We postulate that “system epilepsies” (SystE) are due to an enduring propensity to generate seizures of functionally characterized brain systems. Data supporting this hypothesis—that some types of epilepsy depend on the dysfunction of specific neural ...
Capovilla G. +12 more
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Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven +16 more
wiley +1 more source