Results 111 to 120 of about 33,305 (301)

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

EPİLEPSİ / EPILEPSY

OSMANGAZİ JOURNAL OF MEDICINE, 2016
Özet: Epilepsi; kortikal nöronlardaki anormal ve aşırı elektriksel deşarj sonucu ortaya çıkan, ani, tekrarlayıcı, tanımlanabilen bir olayla tetiklenmemiş epilepsi nöbetleri ile karakterize bir durumdur. Metabolik, toksik, yapısal, enfeksiyöz ve de inflamatuar nedenlerle gerçekleşen, akut santral sinir sistemi (SSS) hasarı nedeni ile ortaya çıkan ...
AKDAĞ, Gönül, ALGIN, Demet, ERDİNÇ, Oğuz   +2 more
openaire   +3 more sources

Early mortality in SCN8A-related epilepsies [PDF]

, 2018
SCN8A-related epilepsies are often severe developmental and epileptic encephalopathies. Seizures can be treatment resistant, and patients suffer from severe intellectual disability.
Møller, Rikke S., Guido Rubboli, Gardella, Elena, Smith, Douglas M., Elena Gardella, Helbig, Ingo, Møller, Rikke S.; id_orcid, Howell, Katherine, Katrine M. Johannesen, Scheffer, Ingrid, Rubboli, Guido, Ingrid Scheffer, Katherine Howell, Ingo Helbig, Rikke S. Møller, Johannesen, Katrine M., Douglas M. Smith   +16 more
core   +1 more source

PROTEOMIC PROFILE MODIFICATIONS IN THE EPILEPTOGENIC NUCLEUS OF THE GENETICALLY AUDIOGENIC SEIZURE-PRONE HAMSTER GASH/SAL AFTER REPEATED SEIZURES

IBRO Neuroscience Reports, 2023
Laura Zeballos Fernández, Carlos García-Peral, Martín Ledesma, Alberto Lazarowski, Dolores López García   +4 more
doaj   +1 more source

Bias‐Field Free Single‐Frequency CW‐ODMR of Nitrogen‐Vacancy Centers in Diamond for the Detection of Transient Electrical Signals

Advanced Materials Interfaces, EarlyView.
Simplified quantum sensing technique for the detection of short electrical signals occurring in neuronal signaling or bioinspired technologies. We demonstrate a single frequency continuous‐wave optically detected magnetic resonance (CW‐ODMR) approach to sense signals that can be as short as 0.2 ms.
João Paulo Silva, Orlando D. Cunha, Pedro Magalhães, Filipe Camarneiro, Jana B. Nieder   +4 more
wiley   +1 more source

Turning up the current – optimizing stimulation parameters with vagus nerve stimulation in a nationwide Norwegian cohort (The NOR-current study)

Brain Stimulation
Background: Despite widespread use of vagus nerve stimulation (VNS), evidence regarding optimal stimulation titration and dosing remains limited.
Konstantin Hrisimirov Kostov, Hrisimir Kostov, Pål Gunnar Larsson, Oliver Henning, Arild Egge, Morten Ingvar Lossius, Jukka Peltola   +6 more
doaj   +1 more source

EPILEPSY [PDF]

The Journal of Nervous and Mental Disease, 1900
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openaire   +2 more sources

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Drosophila melanogaster as a rapid in vivo assay system for preclinical anti‐seizure medication testing

Epilepsia Open
Epilepsy represents a significant medical challenge, with a third of patients failing to achieve seizure freedom despite the use of multiple different anti‐seizure medications (ASM). Drug resistance is common in genetically caused epilepsies.
Emma V. Töfflinger, Konstantin L. Makridis, M.‐Marcel Heim, David Owald, Angela M. Kaindl   +4 more
doaj   +1 more source