Results 101 to 110 of about 974,404 (311)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Clinical characteristics, treatment patterns, and seizure control among children with focal and generalized epilepsy at a tertiary hospital in Tanzania: A cross-sectional secondary analysis.

open access: yesPLoS ONE
This study aimed to describe the clinical characteristics and treatment patterns of children with focal and generalized epilepsy and to identify factors associated with seizure control at a tertiary hospital in Tanzania.
Erneus Ernest
doaj   +1 more source

Overview: Idiopathic Generalized Epilepsies [PDF]

open access: yesEpilepsia, 2003
Summary: The idiopathic generalized epilepsies (IGEs) are an underemphasized topic. Two reasons for this relative lack of attention are that these epilepsies tend to be more easily controlled than the symptomatic partial and generalized epilepsies, and they are not as common.
openaire   +2 more sources

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

open access: yesAdvanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia   +4 more
wiley   +1 more source

Electrophysiologic Study of Cognitive Functions in Epileptic Patients

open access: yesمجلة كلية الطب, 2011
Background: Cognitive dysfunctions in epileptic patients may develop due to the neurophysiologic changes related to seizures or antiepileptic drugs. Objectives: The aim of this longitudinal study was to evaluate the cognitive dysfunction in epileptic ...
Shaymaa J. Mohammed   +2 more
doaj   +1 more source

Management of epilepsy [PDF]

open access: yes, 1989
Figures for the incidence of epilepsy in Malta are not available. The overall figure for epilepsy given by the Royal College of General Practitioners (Reid 1960) is 4.82 per 1,000 population.
Galea Debono, Anthony
core  

Genetic Causes of Generalized Epilepsies [PDF]

open access: yesSeminars in Neurology, 2015
Generalized epilepsies, particularly the idiopathic or genetic generalized epilepsies (GGEs), represent some of the most common epilepsies. Clinical genetic data including family studies and twin studies provide compelling evidence for a prominent genetic impact.
openaire   +2 more sources

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

open access: yesAdvanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu   +7 more
wiley   +1 more source

Genetic Variation in Calcium Channel Gene in Idiopathic Generalized Epilepsies

open access: yesPediatric Neurology Briefs, 2008
Researchers at Women's And Children's Hospital, North Adelaide, and other centers in Australia and Canada screened 240 individuals from 167 families with idiopathic generalized epilepsy and generalized epilepsy with febrile seizures plus (GEFS + ) and 95
J Gordon Millichap
doaj   +1 more source

Self-concept and gender effects in Korean adolescents with epilepsy

open access: yes, 2016
PURPOSE: We aimed to determine whether adolescents with epilepsy (AWE) have a compromised self-concept, whether a lower self-concept is related to mental health, and whether there are sex differences in self-concept in AWE.
엄소용
core   +1 more source

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