Results 1 to 10 of about 69,249 (312)
Neurobiology of Disease, 2023 Generalized epilepsy affects 24 million people globally; at least 25% of cases remain medically refractory. The thalamus, with widespread connections throughout the brain, plays a critical role in generalized epilepsy.
Britta E. Lindquist +3 more
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Clinical characteristics, treatment patterns, and seizure control among children with focal and generalized epilepsy at a tertiary hospital in Tanzania: A cross-sectional secondary analysis. [PDF]
PLoS ONEThis study aimed to describe the clinical characteristics and treatment patterns of children with focal and generalized epilepsy and to identify factors associated with seizure control at a tertiary hospital in Tanzania.
Erneus Ernest
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Management and outcomes among older adults with generalized epilepsy in routine clinical practice [PDF]
Epilepsia OpenGeneralized epilepsy is classically thought of as a disease of the young and adolescent, with rarely reported cases among older adults. We aimed to analyze management and outcomes in a population sparsely described in the literature through a ...
MarieElena Byrnes +2 more
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Frontiers in Neurology, 2022 According to the latest operational 2017 ILAE classification of epileptic seizures, the generalized epileptic seizure is still conceptualized as “originating at some point within and rapidly engaging, bilaterally distributed networks.” In contrast, the ...
Thandar Aung +2 more
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Correlation of sleep macrostructure parameters and idiopathic epilepsies [PDF]
Arquivos de Neuro-Psiquiatria, 2002 Sleep and epilepsy share some common mechanisms. The objective of the present investigation was to study the macrostructure of sleep in patients with idiopathic epilepsies, focal and generalized, comparing these two groups to each other and to a control ...
José Roberto Santiago Barreto +2 more
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A natural marmoset model of genetic generalized epilepsy
Molecular Brain, 2022 Epilepsy has been extensively studied as a common neurological disease. Efforts have been made on rodent and other animal models to reveal the pathogenic mechanisms of epilepsy and develop new drugs for treatment.
Xiangyu Yang +10 more
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Auras in generalized epilepsy [PDF]
Neurology, 2014 We studied the frequency of auras in generalized epilepsy (GE) using a detailed semistructured diagnostic interview.In this cross-sectional study, participants with GE were drawn from the Epilepsy Phenome/Genome Project (EPGP). Responses to the standardized diagnostic interview regarding tonic-clonic (grand mal) seizures were then examined.
Dugan, Patricia +5 more
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Genetic generalized epilepsies [PDF]
Epilepsia, 2018 SummaryThe genetic generalized epilepsies (GGEs) are mainly genetically determined disorders. Although inheritance in most cases appears to be complex, involving multiple genes, variants of a number of genes are known to contribute. Pathogenic variants of SLC2A1 leading to autosomal‐dominant GLUT1 deficiency account for up to 1% of cases, increasing to
Saul A. Mullen, Samuel F. Berkovic
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Febrile Seizures in Idiopathic/Genetic Generalized and Self-Limited Focal Epilepsies
Archives of Epilepsy, 2021 Objectives:Febrile seizure (FS) is the most common form of childhood seizures. Furthermore, idiopathic/generalized and focal/self-limited epilepsies present at the similar age-range. They usually have a favorable outcome.
Feray BÖLÜKBAŞI TÜMAY +4 more
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Frontiers in Human Neuroscience, 2022 Epilepsy types differ by pathophysiology and prognosis. Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive treatment option in epilepsy. Nevertheless, its mode of action and impact on different types of epilepsy are still unknown.
Randi von Wrede +10 more
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