Results 1 to 10 of about 168,970 (253)

Olfactory function in focal epilepsies: Understanding mesial temporal lobe epilepsy beyond the hippocampus [PDF]

Epilepsia Open, 2019
Several lines of research have linked olfactory regions with the pathophysiology of focal epilepsies. Among those regions, the piriform cortex represents the major part of the primary olfactory cortex.
Camilo Espinosa‐Jovel, Rafael Toledano, Adolfo Jiménez‐Huete, Ángel Aledo‐Serrano, Irene García‐Morales, Pablo Campo, Antonio Gil‐Nagel   +6 more
doaj   +3 more sources

Invasive nasal histiocytic sarcoma as a cause of epilepsy [PDF]

Journal of Feline Medicine and Surgery Open Reports, 2018
Case summary A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity.
Koen M Santifort, Ben Jurgens, Guy CM Grinwis, Ingrid Gielen, Björn P Meij, Paul JJ Mandigers   +5 more
doaj   +2 more sources

Surgical Considerations of Intractable Mesial Temporal Lobe Epilepsy

Brain Sciences, 2018
Surgery of temporal lobe epilepsy is the best opportunity for seizure freedom in medically intractable patients. The surgical approach has evolved to recognize the paramount importance of the mesial temporal structures in the majority of patients with ...
Warren W. Boling
doaj   +2 more sources

Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections. [PDF]

Brain : a journal of neurology, 2016
Temporal lobe epilepsy, the most prevalent form of chronic focal epilepsy, is associated with a high prevalence of cognitive impairment but the responsible underlying pathological mechanisms are unknown.
X. Tai, M. Koepp, J. Duncan, Nick C Fox, P. Thompson, S. Baxendale, Joan Y. W. Liu, C. Reeves, Z. Michalak, M. Thom   +9 more
semanticscholar   +4 more sources

Preoperative automated fibre quantification predicts postoperative seizure outcome in temporal lobe epilepsy [PDF]

Brain : a journal of neurology, 2016
Approximately one in every two patients with pharmacoresistant temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe surgery. The reasons for this are unknown and are likely to be multifactorial.
S. Keller, S. Keller, S. Keller, G. Glenn, B. Weber, Barbara A. K. Kreilkamp, Barbara A. K. Kreilkamp, J. Jensen, J. Helpern, J. Wagner, J. Wagner, G. Barker, M. Richardson, M. Richardson, L. Bonilha   +14 more
semanticscholar   +4 more sources

Drug-resistant frontal lobe epilepsy: A review [PDF]

SAGE Open Medicine
Drug-resistant frontal lobe epilepsy is a challenge in epilepsy surgery because it is the second most common epilepsy type after temporal lobe epilepsy.
Mohammed Alshurem
doaj   +2 more sources

Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus

Scientific Reports, 2017
There is a need for diagnostic biomarkers of epilepsy and status epilepticus to support clinical examination, electroencephalography and neuroimaging. Extracellular microRNAs may be potentially ideal biomarkers since some are expressed uniquely within ...
Rana Raoof, Eva M. Jimenez-Mateos, Sebastian Bauer, Björn Tackenberg, Felix Rosenow, Johannes Lang, Müjgan Dogan Onugoren, Hajo Hamer, Tessa Huchtemann, Peter Körtvélyessy, Niamh M. C. Connolly, Shona Pfeiffer, Jochen H. M. Prehn, Michael A. Farrell, Donncha F. O’Brien, David C. Henshall, Catherine Mooney   +16 more
doaj   +2 more sources

Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A [PDF]

, 2013
Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial temporal lobe ...
Alhusaini, S, Becker, A, Becker, F, Berkovic, SF, Blumcke, I, Buchfelder, M, Buono, RJ, Catarino, CB, Cavalleri, GL, Chaves, J, Coras, R, Costa, PP, da Silva, AM, Dahl, HH, de Graan, PN, Delanty, N, Depondt, C, Doherty, CP, Dorn, T, Duncan, S, Eriksson, KJ, Gruber-Sedlmayr, U, Hakonarson, H, Hallmann, K, Hamer, HM, Hansen, J, Hessel, EV, Hildebrand, MS, Kantanen, AM, Kasperaviciute, D, Kobow, K, Koeleman, BP, Krämer, G, Kunz, WS, Kälviäinen, RK, Leal, B, Lerche, H, Leu, C, Matarin, M, Meng Tan, K, Novy, J, O'Brien, TJ, Pandolfo, M, Paravidino, R, Petrovski, S, Ramasamy, A, Reif, PS, Reinthaler, EM, Robbiano, A, Rosenow, F, Ryten, M, Rössler, K, Scheffer, IE, Schlachter, K, Schoch, S, Silva, BM, Sisodiya, SM, Smith, C, Sperling, MR, Steinhoff, BJ, Stogmann, E, Striano, P, Théâtre, E, Tostevin, A, Trabzuni, D, UK Brain Expression Consortium, The, von Lehe, M, Weale, ME, Weber, Y, Zara, F, Zimprich, F, Zumsteg, D   +71 more
core   +9 more sources

Whole-brain functional correlates of memory formation in mesial temporal lobe epilepsy

NeuroImage: Clinical, 2021
The mesial temporal lobe is a key region for episodic memory. Accordingly, memory impairment is frequent in patients with mesial temporal lobe epilepsy. However, the functional relevance of potentially epilepsy-induced reorganisation for memory formation
Anna Doll, Martin Wegrzyn, Anissa Benzait, Markus Mertens, Friedrich G. Woermann, Kirsten Labudda, Christian G. Bien, Johanna Kissler   +7 more
doaj   +1 more source

Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy

Neural Regeneration Research, 2023
Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal sclerosis. There is no effective treatment for cognitive impairment.
Junzi Chen, Yu Wang, Cong Chen, Qingyang Zhang, Shuang Wang, Yi Wang, Jiajia Fang, Ying Wang   +7 more
doaj   +1 more source