Results 11 to 20 of about 133,415 (261)

Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus

Scientific Reports, 2017
There is a need for diagnostic biomarkers of epilepsy and status epilepticus to support clinical examination, electroencephalography and neuroimaging. Extracellular microRNAs may be potentially ideal biomarkers since some are expressed uniquely within ...
Rana Raoof, Eva M. Jimenez-Mateos, Sebastian Bauer, Björn Tackenberg, Felix Rosenow, Johannes Lang, Müjgan Dogan Onugoren, Hajo Hamer, Tessa Huchtemann, Peter Körtvélyessy, Niamh M. C. Connolly, Shona Pfeiffer, Jochen H. M. Prehn, Michael A. Farrell, Donncha F. O’Brien, David C. Henshall, Catherine Mooney   +16 more
doaj   +2 more sources

The Kainic Acid Models of Temporal Lobe Epilepsy

eNeuro, 2021
Experimental models of epilepsy are useful to identify potential mechanisms of epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) model is one of the most commonly used.
E. Rusina, C. Bernard, A. Williamson
semanticscholar   +1 more source

Temporal Lobe Epilepsy and Psychiatric Comorbidity

Frontiers in Neurology, 2021
Most focal seizures originate in the temporal lobe and are commonly divided into mesial and lateral temporal epilepsy, depending upon the neuronal circuitry involved.
Valerio Vinti, G. Dell’Isola, Giorgia Tascini, Elisabetta Mencaroni, G. Cara, P. Striano, A. Verrotti   +6 more
semanticscholar   +1 more source

Mesial temporal lobe epilepsy with hippocampal sclerosis

Definitions, 2020
Mesial temporal lobe epilepsy with hippocampal sclerosis is a rare epilepsy syndrome defined by seizures originating in limbic areas of the mesial temporal lobe, particularly in the hippocampus, amygdala, and in the parahippocampal gyrus and its ...

semanticscholar   +1 more source

A disinhibitory nigra-parafascicular pathway amplifies seizure in temporal lobe epilepsy

Nature Communications, 2020
The precise circuit of the substantia nigra pars reticulata (SNr) involved in temporal lobe epilepsy (TLE) is still unclear. Here we found that optogenetic or chemogenetic activation of SNr parvalbumin+ (PV) GABAergic neurons amplifies seizure activities
Bin Chen, Ceng-lin Xu, Yi Wang, Wenkai Lin, Ying Wang, Liying Chen, Heming Cheng, Lingyu Xu, Tingting Hu, Junli Zhao, Ping Dong, Yi Guo, Shihong Zhang, Shuang Wang, Yudong Zhou, Weiwei Hu, S. Duan, Zhong Chen   +17 more
semanticscholar   +1 more source

Temporal lobe epilepsy and bipolar disorder: a case report

Psychiatry and Behavioral Sciences, 2011
Temporal lobe epilepsy is a neuropsychiatric condition that can present with many psychiatric symptoms. Patients suffering from temporal lobe epilepsy may experience many cognitive, emotional, and behavioral problems between episodes leading to a need ...
Bulent Bahceci, Ayşe Koroğlu, Hulya Guveli, Cicek Hocaoğlu, Murat Aslan, O. Lutfi Gundoğdu   +5 more
doaj   +1 more source

Algebraic relationship between the structural network’s Laplacian and functional network’s adjacency matrix is preserved in temporal lobe epilepsy subjects

NeuroImage, 2021
The relationship between anatomic and resting state functional connectivity of large-scale brain networks is a major focus of current research. In previous work, we introduced a model based on eigen decomposition of the Laplacian which predicts the ...
Farras Abdelnour, Michael Dayan, Orrin Devinsky, Thomas Thesen, Ashish Raj   +4 more
doaj   +1 more source

Temporal lobe epilepsy surgical outcomes can be inferred based on structural connectome hubs: a machine learning study

Annals of Neurology, 2020
Medial temporal lobe epilepsy (TLE) is the most common form of medication‐resistant focal epilepsy in adults. Despite removal of medial temporal structures, more than one‐third of patients continue to have disabling seizures postoperatively.
E. Gleichgerrcht, S. Keller, D. Drane, B. Munsell, K. Davis, E. Kaestner, B. Weber, S. Krantz, W. Vandergrift, J. Edwards, C. McDonald, R. Kuzniecky, L. Bonilha   +12 more
semanticscholar   +1 more source

Surgical Considerations of Intractable Mesial Temporal Lobe Epilepsy

Brain Sciences, 2018
Surgery of temporal lobe epilepsy is the best opportunity for seizure freedom in medically intractable patients. The surgical approach has evolved to recognize the paramount importance of the mesial temporal structures in the majority of patients with ...
Warren W. Boling
doaj   +1 more source

The effect of anxiety on the parameters of carpal tapping in patients with post-stroke epilepsy

Эпилепсия и пароксизмальные состояния, 2020
Aim. To study the characteristics of carpal tapping in the normal condition and the effect of subclinical anxiety on its parameters with post-stroke epilepsy in adults.Material and methods. We examined 140 people aged from 22 to 55 years.
E. A. Narodova, N. A. Shnayder, V. V. Narodova, E. E. Erahtin, D. V. Dmitrenko   +4 more
doaj   +1 more source