Results 31 to 40 of about 733,442 (314)

Optogenetic inhibition of chemically induced hypersynchronized bursting in mice

open access: yesNeurobiology of Disease, 2014
Synchronized activity is common during various physiological operations but can culminate in seizures and consequently in epilepsy in pathological hyperexcitable conditions in the brain.
Fredrik Berglind   +9 more
doaj   +1 more source

Lamotrigine (Sazar) in the treatment of epilepsy: four years of experience in Svt. Luka's Association of Medical institutions for the Diagnosis, Treatment, and Rehabilitation of Nervous System Diseases and Epilepsy

open access: yesРусский журнал детской неврологии, 2022
Aim. To assess the efficacy and tolerability of lamotrigine (Sazar) for various forms of epilepsy, based on long-term experience of Svt. Luka's Association of Medical Institutions for the Diagnosis, Treatment, and Rehabilitation of Nervous System ...
K. Yu. Mukhin   +3 more
doaj   +1 more source

The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]

open access: yes, 2020
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco   +4 more
core   +1 more source

Surgical treatment of pediatric intractable frontal lobe epilepsy due to malformation of cortical development

open access: yesActa Epileptologica, 2022
Background Malformation of cortical development (MCD) is a common cause of intractable epilepsy in children. In this study, the effectiveness of frontal lobe epilepsy (FLE) surgery in children with intractable epilepsy due to MCD was assessed and its ...
Hao Yu   +10 more
doaj   +1 more source

Seizure clusters in drug-resistant focal epilepsy. [PDF]

open access: yes, 2016
We investigated clinical factors associated with seizure clustering in patients with drug-resistant focal epilepsy and any association between seizure clustering and outcome after surgery.
Asadi-Pooya   +12 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Demonstration project on epilepsy in Brazil - Outcome assessment [PDF]

open access: yes, 2007
Purpose: To assess the outcome of patients with epilepsy treated at primary care health units under the framework of the demonstration project on epilepsy in Brazil, part of the WHO/ILAE/IBE Global Campaign Against Epilepsy. Method.
Borges, K   +13 more
core   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Epilepsy Secondary to a Giant AVM: A Case Report

open access: yesCase Reports in Vascular Medicine
Intracranial arteriovenous malformations (AVMs) are vascular anomalies that can present with intracranial hemorrhage, seizures, or neurological deficits.
Emilio García Gómez   +5 more
doaj   +1 more source

Strategies for epilepsy control in public health aspects

open access: yesActa Epileptologica, 2019
This article provides the authors’ recommendations of strategies for epilepsy control in public health aspects. Besides a brief review of some collaborative epilepsy control activities in public health aspects by the International League against Epilepsy
Shichuo Li, Ding Ding, Xiaoyan Liu
doaj   +1 more source

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