Results 101 to 110 of about 2,852,642 (351)

Subcentimeter epilepsy surgery targets by resting state functional magnetic resonance imaging can improve outcomes in hypothalamic hamartoma

open access: yesEpilepsia, 2018
The purpose of this study is to investigate the outcomes of epilepsy surgery targeting the subcentimeter‐sized resting state functional magnetic resonance imaging (rs‐fMRI) epileptogenic onset zone (EZ) in hypothalamic hamartoma (HH).
Varina L. Boerwinkle   +16 more
semanticscholar   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

open access: yesAdvanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang   +17 more
wiley   +1 more source

Epilepsy surgery in bifrontal injury from prior craniopharyngioma resections

open access: yesEpilepsy and Behavior Case Reports, 2014
Epilepsy surgery in frontal lobe epilepsy (FLE) has less favorable seizure-free outcomes than temporal lobe epilepsies. Possible contributing factors include fast propagation patterns and large clinically silent areas which are characteristics of the ...
Monisha Goyal   +4 more
doaj   +1 more source

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

open access: yesAdvanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui   +8 more
wiley   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

open access: yesAdvanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang   +3 more
wiley   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

open access: yesAdvanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi   +3 more
wiley   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

open access: yesAdvanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh   +17 more
wiley   +1 more source

Optimising epilepsy surgery

open access: yesThe Lancet Neurology, 2023
Duncan, JS, Taylor, PN
openaire   +3 more sources

Response: Predicting mood decline following temporal lobe epilepsy surgery in adults

open access: green, 2021
Christine Doherty   +10 more
openalex   +2 more sources

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