Results 81 to 90 of about 82,453 (313)
Implications of genetic diagnostics in epilepsy surgery candidates: A single-center cohort study [PDF]
, 2019 Objective: Genetic causes are increasingly identified in patients with focal epilepsy. These genetic causes may be related to the effectiveness of epilepsy surgery. We aimed to assess the use and yield of genetic testing in a large cohort of patients who
the Dutch Collaborative Epilepsy Surgery Program (LWEC)
core
Advanced Science, EarlyView.Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang +13 more
wiley +1 more source
Update on surgery for epilepsy [PDF]
Archives of Disease in Childhood, 1999 Surgery for epilepsy is not new, it has been performed for over 100 years. However, there has been a reluctance to consider young children for surgery other than in exceptional circumstances, owing in part to the invasive nature of the presurgical evaluation. Recent advances in investigative techniques have allowed identification of candidates early in
openaire +2 more sources
In vivo P-glycoprotein function before and after epilepsy surgery [PDF]
, 2014 Objectives: To study the functional activity of the multidrug efflux transporter P-glycoprotein (Pgp) at the blood-brain barrier of patients with temporal lobe epilepsy using (R)-[11C]verapamil (VPM)-PET before and after temporal lobe surgery to assess ...
Liu, J.Y.W. +12 more
core +1 more source
Testing an online screening tool for epilepsy surgery evaluation
Arquivos de Neuro-PsiquiatriaBackground Epilepsy surgery is recognized for its effectiveness in controlling seizures in a significant number of patients with drug-resistant epilepsy.
Bianca Cecchele Madeira +6 more
doaj +1 more source
Advanced Science, EarlyView.Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
Long-Term Seizure and Antiepileptic Drug Outcomes After Epilepsy Surgery in Adults [PDF]
, 2015 Epilepsy surgery is an effi cacious treatment for selected persons with drug-resistant focal epilepsy, rendering many seizure-free and others signifi cantly improved.
Edelvik, Anna, +5 more
core +1 more source
Insular epilepsy surgery [PDF]
Epilepsia, 2017 SummarySince it was originally described nearly 70 years ago, insular epilepsy has been increasingly recognized and may explain failures after apparently well‐planned operations. We review the history of awareness of the phenomenon, techniques for its assessment, and its surgical management.
Pramote, Laoprasert +2 more
openaire +2 more sources
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
No apparent effect of surgery for temporal lobe epilepsy on heart rate variability [PDF]
, 2006 BACKGROUND: Impaired cardiac autonomic function may contribute to the risk of sudden unexpected death in epilepsy (SUDEP). Clinical observations indicate that successful epilepsy surgery is associated with a reduced risk of SUDEP.
Tomson, T. +7 more
core +1 more source