Results 141 to 150 of about 1,687,814 (309)

Current state of the art of traditional and minimal invasive epilepsy surgery approaches

Brain and Spine
Introduction: Open resective surgery remains the main treatment modality for refractory epilepsy, but is often considered a last resort option due to its invasiveness.
Fabian Winter, Marie T. Krueger, Daniel Delev, Tom Theys, Dirk MP Van Roost, Kostas Fountas, Olaf E.M.G. Schijns, Karl Roessler   +7 more
doaj   +1 more source

The impact of medication shortages on paediatric care: A retrospective impact analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg, Laurens Christiaan van Rijn, Elisabeth Johanna Ruijgrok, Sinno Henricus Paulus Simons, Brigitta Carolina Maria Witjes, Jan‐Dietert Christoffer Brugma, Robert Bernard Flint   +6 more
wiley   +1 more source

Implementing an epilepsy surgery center. Initial experience at a university hospital in Brazil

Arquivos de Neuro-Psiquiatria
Epilepsy is a serious neurological condition, often without a full and effective treatment. In some cases, surgery is beneficial, despite being underused.
Gabriel Pereira Escudeiro, Rafael Teixeira Magalhães Leal, Heros Henrique Melo de Almeida, Marcus Andre Aciolly, José Alberto Landeiro, Bruno Lima Pessoa   +5 more
doaj   +1 more source

Intelligence two years after epilepsy surgery in children. [Elektronisk resurs]

, 2013
Intelligence before and two years after epilepsy surgery was assessed in 94 children and adolescents and related to preoperative IQ and seizure outcome. The median full-scale IQ was 70 before and two years after surgery.
Viggedal, Gerd,, Carlsson, Göran,, Uvebrant, Paul,, Olsson, Ingrid,, Rydenhag, Bertil,   +4 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

What's a White Matter ‘Fiber’?

Clinical Anatomy, EarlyView.
ABSTRACT White matter anatomy is investigated using methods that operate at markedly different spatial scales and rely on distinct biological and physical principles. Nevertheless, the term “fiber” is routinely applied to the outputs of tract‐tracing studies, diffusion MRI tractography, and postmortem fiber dissection, often as though these entities ...
Guillaume Dannhoff, Frederic Andersson, Christophe Destrieux, Igor Lima Maldonado   +3 more
wiley   +1 more source

Siblings With Duchenne Muscular Dystrophy: Exploring Diagnosis Age and Disease Progression in a Genetic Therapy‐Naïve Cohort

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Duchenne muscular dystrophy (DMD) is the most common pediatric muscular dystrophy. Typically, there is a ~ 2‐year delay between symptom onset and diagnosis. Limited data on outcomes in early‐diagnosed individuals have limited the understanding of the clinical impact of early diagnosis.
Vaishnavi Brahmamdam, Cuixia Tian, Niki Armstrong, Valentina Pilipenko, Lisa J. Martin, Alexander Zygmunt, Irina Rybalsky, Lisa Reebals, Chinmayee B. Nagaraj   +8 more
wiley   +1 more source

Outcomes after resective epilepsy surgery in patients over 50 years of age in Sweden 1990-2009-A prospective longitudinal study

, 2014
PurposeMost epilepsy surgery candidates are young adults. Outcome reports after epilepsy surgery in patients ≥50 years are few and varying. The aim of this study was to describe patient characteristics of older compared to younger adults and analyse ...
Flink, R., Malmgren, Kristina, Bialek, Fatima, Rydenhag, Bertil, Bialek, Fatima,, Malmgren, Kristina,, Rydenhag, Bertil,, Flink, Roland,   +7 more
core   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata, Chhitij Tiwari, Zheng Fan, Muge Gucsavas‐Calikoglu, Yael Shiloh‐Malawsky, Kimberly S. Foss, Stephanie N. Peck, Erin L. Heinzen, Chon Lee, Senyene E. Hunter   +9 more
wiley   +1 more source

Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery. [PDF]

Epilepsia
Abstract Objective Resective surgery achieves seizure freedom in approximately 60%–80% of patients with drug‐resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear.
Cavender AC, Doss DJ, Makhoul GS, Lerma BHM, Reda A, Withers CP, Liao E, Wang K, González HFJ, Goodale SE, Johnson GW, Cutting LE, Bick SK, Chang C, Morgan VL, Englot DJ.   +15 more
europepmc   +2 more sources