Results 1 to 10 of about 74,202 (303)

Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy

open access: yesEpilepsy and Behavior Case Reports, 2018
Responsive neurostimulation for epilepsy involves an implanted device that delivers direct electrical brain stimulation in response to detection of incipient seizures.
Nilika S. Singhal   +6 more
doaj   +1 more source

An impact of the EpiTapp® application on the quality of life of patients with drug-resistant structural focal epilepsy

open access: yesЭпилепсия и пароксизмальные состояния, 2023
Background. One of the main goals of rehabilitation programs is to improve the quality of life (QoL) of patients with various chronic diseases, including epilepsy.
E. А. Narodova   +3 more
doaj   +1 more source

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

open access: yes, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun   +3 more
core   +1 more source

Pregabalin Add-On vs. Dose Increase in Levetiracetam Add-On Treatment: A Real-Life Trial in Dogs With Drug-Resistant Epilepsy

open access: yesFrontiers in Veterinary Science, 2022
Epilepsy is a common neurological disorder affecting 0.6–0.75% of dogs in veterinary practice. Treatment is frequently complicated by the occurrence of drug-resistant epilepsy and cluster seizures in dogs with idiopathic epilepsy.
Sandra R. P. Kriechbaumer   +12 more
doaj   +1 more source

Hypotheses of development and strategies for overcoming drug resistance in epilepsy. Part I: Hypotheses of development

open access: yesЭпилепсия и пароксизмальные состояния
Currently, the problem of effective therapy for drug-resistant epilepsy remains vastly relevant. The severity of drug-resistant epilepsy, remarkable negative social sequelae and sudden death in epilepsy pose a heavy burden on healthcare system.
A. M. Yakimov   +6 more
doaj   +1 more source

Early epilepsy surgery for non drug-resistant patients

open access: yesEpilepsy & Behavior Reports, 2022
The aim of epilepsy treatment is to achieve seizure freedom. Surgery is often still considered a late option when pharmacological treatments have failed and epilepsy has become drug-resistant.We analyse the clinical features and surgical outcome in ...
Veronica Pelliccia   +6 more
doaj   +1 more source

White Matter Abnormalities in Patients with Treatment-Resistant Genetic Generalized Epilepsies. [PDF]

open access: yes, 2016
BACKGROUND Genetic generalized epilepsies (GGEs) are associated with microstructural brain abnormalities that can be evaluated with diffusion tensor imaging (DTI). Available studies on GGEs have conflicting results.
Allendorfer, Jane B   +7 more
core   +2 more sources

Clobazam as an Add-on Therapy of Patients with Drug-resistant Epilepsy: Experience of a Tertiary Epilepsy Center

open access: yesArchives of Epilepsy, 2020
Objectives:This retrospective study aimed to overview the efficacy and side effects of clobazam in patients with drug-resistant epilepsy who were followed in a tertiary epilepsy center.Methods:The patients who had been started clobazam as add-on therapy ...
Nermin Görkem ŞİRİN   +2 more
doaj   +1 more source

Psychiatric symptoms and comorbidities in patients with drug-resistant epilepsy in presurgical assessment—A prospective explorative single center study

open access: yesFrontiers in Psychiatry, 2022
IntroductionPeople with epilepsy (PWE) have a higher prevalence of psychiatric disorders. Some individuals with drug-resistant epilepsy might benefit from surgical interventions.
Fabian Friedrich   +6 more
doaj   +1 more source

Evaluation of perampanel as monotherapy for focal seizures: Experience from open-label extension studies [PDF]

open access: yes, 2017
Perampanel, a selective, non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is approved for adjunctive treatment of focal seizures, with or without secondarily generalized seizures, and for primary ...
Cartwright, Karen   +5 more
core   +1 more source

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