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Neuromodulation in Drug Resistant Epilepsy [PDF]
Aging and disease, 2021 Epilepsy affects approximately 70 million people worldwide, and it is a significant contributor to the global burden of neurological disorders. Despite the advent of new AEDs, drug resistant-epilepsy continues to affect 30-40% of PWE. Once identified as having drug-resistant epilepsy, these patients should be referred to a comprehensive epilepsy center
Naymee Velez Ruiz
exaly +3 more sources
Drug-Resistant Epilepsy and Surgery [PDF]
Current Neuropharmacology, 2017 Epilepsy is a chronic brain disease that is caused by various factors and characterized by recurrent, episodic and temporary central nervous system dysfunction which results due to excessive discharge of brain neurons. In the past decades, despite the continuous development of antiepileptic drugs, there are still many patients with epilepsy progressing
Shui Liu, Jiyao Sheng, Bingjin Li
exaly +3 more sources
Introduction to the special issue “Redesigning the hypotheses for drug‐resistant epilepsy”
Epilepsia Open, 2022 Drug‐resistant epilepsy represents an important neurological condition. Its prevalence is not modified in spite of the different hypotheses established to understand the mechanisms involved.
Luisa Rocha
doaj +2 more sources
Epilepsia Open, 2022 More than one‐third of people with epilepsy develop drug‐resistant epilepsy (DRE). Different hypotheses have been proposed to explain the origin of DRE. Accumulating evidence suggests the contribution of neuroinflammation, modifications in the integrity ...
Patricia Campos‐Bedolla +2 more
doaj +3 more sources
Factors associated with drug-resistant epilepsy in adults from Southern Kazakhstan [PDF]
Future Science OAIntroduction The prevalence of drug-resistant epilepsy (DRE) among epilepsy patients has not decreased despite better diagnostic methods and treatment options because it affects approximately one-third of all epilepsy patients.
Gulzira Baimakhanova +11 more
doaj +2 more sources
Surgery for drug-resistant focal epilepsy
Annals of Indian Academy of Neurology, 2014 During the colloquium on drug-resistant epilepsy (DRE) at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore on August 16-18, 2013, a number of presentations were made on the surgically remediable lesional epilepsy syndromes ...
Malla Bhaskara Rao +6 more
doaj +3 more sources
Early epilepsy surgery for non drug-resistant patients
Epilepsy & Behavior Reports, 2022 The aim of epilepsy treatment is to achieve seizure freedom. Surgery is often still considered a late option when pharmacological treatments have failed and epilepsy has become drug-resistant.We analyse the clinical features and surgical outcome in ...
Veronica Pelliccia +6 more
doaj +3 more sources
Metabolomics As a Tool for the Characterization of Drug-Resistant Epilepsy [PDF]
Frontiers in Neurology, 2017 PURPOSE: Drug resistance is a critical issue in the treatment of epilepsy, contributing to clinical emergencies and increasing both serious social and economic burdens on the health system. The wide variety of potential drug combinations followed by often failed consecutive attempts to match drugs to an individual patient may mean that this treatment ...
Luigi Atzori +2 more
exaly +7 more sources
Epilepsia Open, 2023 Objective We analyzed trends in patients' characteristics, outcomes, and waiting times over the last 25 years at our epilepsy surgery center situated in Central Europe to highlight possible areas of improvement in our care for patients with drug ...
Vít Všianský +13 more
doaj +1 more source
SAGE Open Medicine, 2022 Objective: This study aims to evaluate knowledge and awareness toward surgical treatment of epilepsy among medical students at Umm Al-Qura University.
Rami Algahtani +7 more
doaj +1 more source