Results 31 to 40 of about 2,772,421 (294)
Assessment of clinical risk factors for drug-resistant epilepsy in children and teenagers [PDF]
, 2014 Introduction: Epilepsy is one of the most common neurological illnesses occurring in children. In approximately 20–30% of cases it is drug-resistant.
Janusz Wendorff +2 more
core +1 more source
The Association Between STX1B Polymorphisms and Treatment Response in Patients With Epilepsy
Frontiers in Pharmacology, 2021 Background: Epilepsy is a debilitating brain disease with complex inheritance and frequent treatment resistance. However, the role of STX1B single nucleotide polymorphisms (SNPs) in epilepsy treatment remains unknown.Objective: This study aimed to ...
Shitao Wang +11 more
doaj +1 more source
PLoS ONE, 2023 This study sought to identify differences in cannabis use and perceptions about cannabis in mitigating seizure-related symptoms in patients with epilepsy, and to evaluate differences in these patterns between drug-resistant versus pharmacoresponsive ...
Danielle McDermott +5 more
doaj +1 more source
Ketogenic diets for drug-resistant epilepsy [PDF]
Cochrane Database of Systematic Reviews, 2020 Ketogenic diets (KDs) are high in fat and low in carbohydrates and have been suggested to reduce seizure frequency in people with epilepsy. Such diets may be beneficial for children with drug-resistant epilepsy. This is an update of a review first published in 2003, and last updated in 2018.To assess the effects of ketogenic diets for people with drug ...
Martin-McGill, Kirsty J +3 more
openaire +4 more sources
Epilepsia Open, 2023 Objective For people with drug‐resistant epilepsy, the use of epilepsy surgery is low despite favorable odds of seizure freedom. To better understand surgery utilization, we explored factors associated with inpatient long‐term EEG monitoring (LTM), the ...
Chloe E. Hill +6 more
doaj +1 more source
Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence [PDF]
, 2011 Marco Mula1, Dale C Hesdorffer21Department of Clinical and Experimental Medicine, Amedeo Avogadro University and Division of Neurology, University Hospital Maggiore della Carità, Novara, Italy; 2Gertrude H Sergievsky Center and Department of ...
Mula M +3 more
core +1 more source
Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy [PDF]
Brain, 2002 Epilepsy is resistant to drug treatment in about one-third of cases, but the mechanisms underlying this drug resistance are not understood. In cancer, drug resistance has been studied extensively. Amongst the various resistance mechanisms, overexpression of drug resistance proteins, such as multi-drug resistance gene-1 P-glycoprotein (MDR1) and ...
S M, Sisodiya +4 more
openaire +2 more sources
Surgical Management of Drug Resistant Epilepsy [PDF]
Al-Azhar International Medical Journal, 2020 Background: Epilepsy is a disease of the brain defined by any of the following conditions: At least 2 unprovoked (or reflex) seizures occurring more than 24 hours apart; One unprovoked (or reflex) seizure with relatively high recurrence risk (i.e., ≥60% (
Ahmed Gabr
doaj +1 more source
Pathophysiology of drug-resistant canine epilepsy
The Veterinary Journal, 2023 Drug resistance continues to be a major clinical problem in the therapeutic management of canine epilepsies with substantial implications for quality of life and survival times. Experimental and clinical data from human medicine provided evidence for relevant contributions of intrinsic severity of the disease as well as alterations in pharmacokinetics ...
Heidrun, Potschka +3 more
openaire +2 more sources
The Concept of Drug-Resistant Epileptogenic Zone
Frontiers in Neurology, 2019 Resective surgery is the most effective way to treat drug-resistant epilepsy. Despite extensive pre-surgical evaluation, only 30–70% patients would become seizure-free after surgery.
Chunbo Zhang, Patrick Kwan, Patrick Kwan
doaj +1 more source