Results 11 to 20 of about 74,202 (303)
Drug-Resistant Epilepsy and Surgery [PDF]
Current Neuropharmacology, 2017 Epilepsy is a chronic brain disease that is caused by various factors and characterized by recurrent, episodic and temporary central nervous system dysfunction which results due to excessive discharge of brain neurons. In the past decades, despite the continuous development of antiepileptic drugs, there are still many patients with epilepsy progressing
Sheng, Jiyao +4 more
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Surgery for drug-resistant focal epilepsy
Annals of Indian Academy of Neurology, 2014 During the colloquium on drug-resistant epilepsy (DRE) at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore on August 16-18, 2013, a number of presentations were made on the surgically remediable lesional epilepsy syndromes ...
Malla Bhaskara Rao +6 more
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Pathogenesis of drug resistant epilepsy
Эпилепсия и пароксизмальные состояния, 2019 Pharmacotherapy is the first-line treatment modality for epilepsy. However, in 20-40% of patients, epilepsy is resistant to pharmacotherapy. These numbers have not changed for decades despite the development and use of antiepileptic drugs with novel ...
S. M. Malyshev +3 more
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Neuromodulation in Drug Resistant Epilepsy [PDF]
Aging and disease, 2021 Epilepsy affects approximately 70 million people worldwide, and it is a significant contributor to the global burden of neurological disorders. Despite the advent of new AEDs, drug resistant-epilepsy continues to affect 30-40% of PWE. Once identified as having drug-resistant epilepsy, these patients should be referred to a comprehensive epilepsy center
Rincon, Natalia +2 more
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Epilepsia Open, 2023 Objective We analyzed trends in patients' characteristics, outcomes, and waiting times over the last 25 years at our epilepsy surgery center situated in Central Europe to highlight possible areas of improvement in our care for patients with drug ...
Vít Všianský +13 more
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Introduction to the special issue “Redesigning the hypotheses for drug‐resistant epilepsy”
Epilepsia Open, 2022 Drug‐resistant epilepsy represents an important neurological condition. Its prevalence is not modified in spite of the different hypotheses established to understand the mechanisms involved.
Luisa Rocha
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SAGE Open Medicine, 2022 Objective: This study aims to evaluate knowledge and awareness toward surgical treatment of epilepsy among medical students at Umm Al-Qura University.
Rami Algahtani +7 more
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Drug resistance in epilepsy [PDF]
Epilepsia, 2010 SummaryDrug resistance remains one of the major challenges in epilepsy therapy. Identification of factors that contribute to therapeutic failure is crucial for future development of novel drugs and therapeutic strategies for difficult‐to treat epilepsies. For an expanded treatment of this topic see Jasper’s basic mechanisms of the epilepsies.
Jan Gorter, Heidrun Potschka
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The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]
, 2020 Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco +4 more
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Clinical, radiological and electrophysiological predictors for drug-resistant epilepsy
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023 Background Epilepsy is the third chronic brain illness worldwide. About a third of the epileptic patients will be drug resistant. Early identification of these patients is critical for appropriate treatment selection and prevention of the devastating ...
Noha T. Abokrysha +5 more
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