Results 41 to 50 of about 74,202 (303)

Drug Resistant Epilepsy Among Patients Attended The Neurosciences Hospital

مجله كليه طب الكندي, 2019
Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules to achieve sustained seizure freedom. Up to 30% of patients referred to clinics with a diagnosis of
Nael Husain Zaer
doaj   +1 more source

Auras in patients with temporal lobe epilepsy and mesial temporal sclerosis. [PDF]

, 2016
We investigated auras in patients with drug-resistant temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS). We also investigated the clinical differences between patients with MTS and abdominal auras and those with MTS and non-mesial temporal
Asadi-Pooya, Ali Akbar, Nei, Maromi, Sharan, Ashwini, Sperling, Michael R.   +3 more
core   +2 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Effect of neurostimulation on cognition and mood in refractory epilepsy. [PDF]

, 2018
Epilepsy is a common, debilitating neurological disorder characterized by recurrent seizures. Mood disorders and cognitive deficits are common comorbidities in epilepsy that, like seizures, profoundly influence quality of life and can be difficult to ...
Chan, Alvin Y, Chang, Edward F, Rao, Vikram R, Rolston, John D   +3 more
core   +1 more source

Stress regulation in drug-resistant epilepsy [PDF]

Epilepsy & Behavior, 2017
The prevalence of psychological distress, especially depressive and anxiety disorders, is higher in epilepsy than in other chronic health conditions. These comorbid conditions contribute even more than epileptic seizures themselves to impaired quality of life in patients with epilepsy (PWE).
Kotwas, Iliana, Mcgonigal, Aileen, Bastien-Toniazzo, Mireille, Bartolomei, Fabrice, Micoulaud-Franchi, Jean-Arthur   +4 more
openaire   +2 more sources

Mindfulness-based interventions in epilepsy: a systematic review [PDF]

, 2017
Mindfulness based interventions (MBIs) are increasingly used to help patients cope with physical and mental long-term conditions (LTCs). Epilepsy is associated with a range of mental and physical comorbidities that have a detrimental effect on quality of
AM Kanner, AM Kanner, AW Yuen, Bhautesh Jani, BP Hermann, CL Harden, EA Souza de, F Gilliam, J Carmody, J Kabat-Zinn, J Kabat-Zinn, J Kabat-Zinn, J Maguire, J Piet, JE Jones, JLT Dahl, Karen Wood, KM Fiest, KO Nakken, LO Fjorback, M Gandy, M Lawrence, M Lustyk, Maggie Lawrence, MJ Jackson, MP Kerr, NJ Thompson, NJ Thompson, NR Temkin, P Mehndiratta, R Simpson, Robert Simpson, RS Fisher, S Beyenburg, SA Lee, SG Hofmann, SG Hofmann, SR Haut, Stewart W. Mercer, T Betts, T Lundgren, T Lundgren, U Panjwani, V Tang, V Tang, VK Kimiskidis   +45 more
core   +3 more sources

MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy

Frontiers in Pharmacology, 2021
One-third of patients with epilepsy suffer from drug-resistant epilepsy (DRE). Valproic acid (VPA) is a classic anticonvulsant drug, and its resistance is a crucial predictor of DRE, but the pathogenesis remain unknown.
Meng Fu, Yiqing Zhu, Junqi Zhang, Wei Wu, Yunxia Sun, Xuemei Zhang, Jie Tao, Zhiping Li   +7 more
doaj   +1 more source

Validated outcome of treatment changes according to International League Against Epilepsy criteria in adults with drug-resistant focal epilepsy. [PDF]

, 2019
OBJECTIVE: Although many studies have attempted to describe treatment outcomes in patients with drug-resistant epilepsy, results are often limited by the adoption of nonhomogeneous criteria and different definitions of seizure freedom.
Alexandre V, Bajacek M, Berg AT, Berg AT, Berg AT, Callaghan B, Callaghan BC, Carreño M, Gomez‐Alonso J, Hao X, Kwan P, Kwan P, Lhatoo SD, Luciano AL, Mäkinen J, Neligan A, Perucca E, Ramos‐Lizana J, Schiller Y, Téllez‐Zenteno JF, Zaccara G   +20 more
core   +2 more sources

Surgery in Epilepsy – How Advances in Human Neurology Can Benefit Veterinary Patients

Veterinary Evidence, 2016
This article reports the evidence behind pre-surgical evaluation and epilepsy surgery in human patients with drug-resistant idiopathic epilepsy and how this could potentially form the basis for the treatment of canine drug-resistant epilepsy in the ...
Marios Charalambous
doaj   +1 more source

EXPLORING COGNITIVE IMPAIRMENTS IN DRUG-RESISTANT EPILEPSY: INSIGHTS FROM A COMPARATIVE ANALYSIS

Journal of Social Sciences
This article explores the cognitive impairments in individuals with drug-resistant epilepsy compared to those with well-controlled epilepsy. The research involves 102 subjects (62 with drug-resistant epilepsy and 40 with well-controlled epilepsy), and ...
DOTEN, Natalia
doaj   +1 more source