Results 61 to 70 of about 2,582,050 (300)

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Pregabalin Add-On vs. Dose Increase in Levetiracetam Add-On Treatment: A Real-Life Trial in Dogs With Drug-Resistant Epilepsy

open access: yesFrontiers in Veterinary Science, 2022
Epilepsy is a common neurological disorder affecting 0.6–0.75% of dogs in veterinary practice. Treatment is frequently complicated by the occurrence of drug-resistant epilepsy and cluster seizures in dogs with idiopathic epilepsy.
Sandra R. P. Kriechbaumer   +12 more
doaj   +1 more source

Stress regulation in drug-resistant epilepsy [PDF]

open access: yesEpilepsy & Behavior, 2017
The prevalence of psychological distress, especially depressive and anxiety disorders, is higher in epilepsy than in other chronic health conditions. These comorbid conditions contribute even more than epileptic seizures themselves to impaired quality of life in patients with epilepsy (PWE).
Kotwas, Iliana   +4 more
openaire   +4 more sources

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan   +7 more
wiley   +1 more source

Surgery for temporal lobe epilepsy in Semarang,Indonesia: The first 56 patients with follow up longer than 12 months [PDF]

open access: yes, 2006
Until October 2005, surgery were performed for 76 intractable temporal lobe epilepsy patients. Among them, 56 patients had follow-up of 12-76 months. The patients consisted of 35 males and 21 females,age between 3-38 year-old.
Muttaqin, Zainal
core   +2 more sources

Hypotheses of development and strategies for overcoming drug resistance in epilepsy. Part I: Hypotheses of development

open access: yesЭпилепсия и пароксизмальные состояния
Currently, the problem of effective therapy for drug-resistant epilepsy remains vastly relevant. The severity of drug-resistant epilepsy, remarkable negative social sequelae and sudden death in epilepsy pose a heavy burden on healthcare system.
A. M. Yakimov   +6 more
doaj   +1 more source

An impact of the EpiTapp® application on the quality of life of patients with drug-resistant structural focal epilepsy

open access: yesЭпилепсия и пароксизмальные состояния, 2023
Background. One of the main goals of rehabilitation programs is to improve the quality of life (QoL) of patients with various chronic diseases, including epilepsy.
E. А. Narodova   +3 more
doaj   +1 more source

Epilepsy and drug-resistant epilepsy in neurocutaneous syndromes

open access: yesNorthwestern Medical Journal, 2023
Aim: Epilepsy frequently accompanies neurocutaneous syndromes. Due to the comorbid conditions that epileptic seizures may cause, their frequency, type, and duration also affect the prognosis of neurocutaneous diseases. The purpose of this study was to examine the frequency of epilepsy and drug-resistant epilepsy in neurocutaneous syndromes, and factors
Ayşegül Danış, Fatma Hancı
openaire   +2 more sources

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

Recent Aspects of Pediatric Epilepsy Surgery [PDF]

open access: yes, 2019
Surgery has been and is now a well-established treatment indicated for adults and children with drug-resistant epilepsy (DRE). The surgical landscape for children with DRE appears to be expanding, and surgical cases of pediatric epilepsy have increased ...
김흥동
core   +1 more source

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