Results 71 to 80 of about 74,202 (303)

Modern approaches to treating drug-resistant epilepsy - ketogenic diet, innovative drugs and neurosurgery

Quality in Sport
Introduction and objective Drug-resistant epilepsy (DRE) is a type of epilepsy where seizures persist despite treatment with multiple antiepileptic drugs being implemented.
Robert Rzenno, Monika Brzozowska, Wiktoria Wardal, Natalia Furlepa, Karolina Wojciechowska, Marcelina Matuszewska, Katarzyna Wicha, Natalia Sidz, Magdalena Tomaszewska, Wiktoria Jedlikowska   +9 more
doaj   +1 more source

Current approaches to neurosurgical treatment for drug-resistant focal epilepsy in adults

Неврология, нейропсихиатрия, психосоматика, 2018
The review is dedicated to the problems of current neurosurgical treatment for drug-resistant epilepsy in the adult population of Russia and foreign countries. The literature published in the period  2010–2017 was sought in Russian and foreign databases.
E. A. Narodova, A. A. Narodov, N. A. Shnayder, D. V. Dmitrenko, I. G. Strotskaya   +4 more
doaj   +1 more source

Getting the best outcomes from epilepsy surgery. [PDF]

, 2018
Neurosurgery is an underutilized treatment that can potentially cure drug-refractory epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to ensure optimal outcomes.
Duncan, John S, Elger, Christian E, Engel, Jerome, Staba, Richard, Vakharia, Vejay N, Witt, Juri-Alexander   +5 more
core  

Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options. [PDF]

, 2014
Seizures are clinically significant manifestations associated with 79%-90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and ...
Fallah, Aria, Wang, Shelly
core   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Incidence and prevalence of major epilepsy-associated brain lesions

Epilepsy & Behavior Reports, 2022
Epilepsy surgery is an effective treatment option for drug-resistant focal epilepsy patients with associated structural brain lesions. However, little epidemiological data are available regarding the number of patients with these lesions.
Javier A. López-Rivera, Victoria Smuk, Costin Leu, Gaelle Nasr, Deborah Vegh, Arthur Stefanski, Eduardo Pérez-Palma, Robyn Busch, Lara Jehi, Imad Najm, Ingmar Blümcke, Dennis Lal   +11 more
doaj   +1 more source

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. [PDF]

, 2020
Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden unexplained death in epilepsy (SUDEP).
Anvar, Mana, Baraban, Scott C, Griffin, Aliesha, Hamling, Kyla   +3 more
core   +1 more source

Deep brain and cortical stimulation for epilepsy [PDF]

, 2014
Background : Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in invasive intracranial neurostimulation as a treatment for these patients ...
Anderson, Andrade, Becker, Beyenburg, Boon, Borghs, Boëx, Buren, Chabardes, Chkhenkeli, Cramer, Cramer, Curtin, Deeks, Devinsky, Elbourne, Elisevich, Engel, Fisher, Fisher, Fisher, Forsgren, Franzini, Handforth, Hodaie, Jehi, Katariwala, Kellinghaus, Khan, Kwan, Kwan, Kwan, Lim, Lim, McLachlan, Morrell, Neligan, Parrent, Privitera, Raftopoulos, Raftopoulos, Rijckevorsel, Rijckevorsel, Salanova, Schulze-Bonhage, Schulze-Bonhage, Selwa, Stedman, Tellez-Zenteno, Tellez-Zenteno, Tisi, Tomson, Valentin, Velasco, Velasco, Velasco, Velasco, Velasco, Velasco, Vonck, Wiebe, Wille, Wright, Zou   +63 more
core   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source

Association between Genetic Polymorphism of SCN1A, GABRA1 and ABCB1 and Drug Responsiveness in Vietnamese Epileptic Children

Medicina
Background and Objectives: Drug resistant epilepsy (DRE) is a major hurdle in epilepsy, which hinders clinical care, patients’ management and treatment outcomes.
Hai Xuan Tang, Muoi Dang Ho, Nhung Phuong Vu, Hung Vu Cao, Vinh Anh Ngo, Van Thi Nguyen, Thuan Duc Nguyen, Ton Dang Nguyen   +7 more
doaj   +1 more source