Results 21 to 30 of about 74,202 (303)

Ketogenic diets for drug-resistant epilepsy [PDF]

Cochrane Database of Systematic Reviews, 2020
Ketogenic diets (KDs) are high in fat and low in carbohydrates and have been suggested to reduce seizure frequency in people with epilepsy. Such diets may be beneficial for children with drug-resistant epilepsy. This is an update of a review first published in 2003, and last updated in 2018.To assess the effects of ketogenic diets for people with drug ...
Martin-McGill, Kirsty J, Bresnahan, Rebecca, Levy, Robert G, Cooper, Paul N   +3 more
openaire   +4 more sources

Neurostimulation for Drug-Resistant Epilepsy [PDF]

Continuum, 2013
The purpose of this review is to provide an evidence-based update on the neurostimulation options available for patients with drug-resistant epilepsy in the United States and in European countries.The field of neurostimulation for epilepsy has grown dramatically since 1997, when vagus nerve stimulation became the first device to be approved for ...
Christopher M, DeGiorgio, Scott E, Krahl
openaire   +2 more sources

Neuroinflammatory targets and treatments for epilepsy validated in experimental models [PDF]

, 2017
A large body of evidence that has accumulated over the past decade strongly supports the role of inflammation in the pathophysiology of human epilepsy.
Aronica, Eleonora, Bauer, Sebastian, Bozzi, Yuri, Caleo, Matteo, Dingledine, Raymond, Gorter, Jan A., Henshall, David C., Kaminski, Rafal M., Kaufer, Daniela, Koh, Sookyong, Lã¶scher, Wolfgang, Louboutin, Jean-pierre, Mishto, Michele, Norwood, Braxton A., Palma, Eleonora, Poulter, Michael O., Terrone, Gaetano, Vezzani, Annamaria   +17 more
core   +13 more sources

Pathophysiology of drug-resistant canine epilepsy

The Veterinary Journal, 2023
Drug resistance continues to be a major clinical problem in the therapeutic management of canine epilepsies with substantial implications for quality of life and survival times. Experimental and clinical data from human medicine provided evidence for relevant contributions of intrinsic severity of the disease as well as alterations in pharmacokinetics ...
Heidrun, Potschka, Andrea, Fischer, Wolfgang, Löscher, Holger A, Volk   +3 more
openaire   +2 more sources

BEHAVIOURAL PARTICULARITIES OF PATIENTS WITH DRUG-RESISTANT EPILEPSY: A COMPARATIVE STUDY [PDF]

Psihologie
This study examines the behavioral particularities of individuals with epilepsy, focusing on aggression, hostility, and shyness in patients with drug-resistant epilepsy compared to those with well-controlled epilepsy.
Natalia DOȚEN
doaj   +1 more source

Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]

, 2014
Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M, Gornbein, Jeffrey, Harper, Ronald, Meymandi, Sheba, Miller, Patrick R, Schrader, Lara, Soss, Jason   +6 more
core   +1 more source

Seizure clusters in drug-resistant focal epilepsy. [PDF]

, 2016
We investigated clinical factors associated with seizure clustering in patients with drug-resistant focal epilepsy and any association between seizure clustering and outcome after surgery.
Asadi-Pooya, Asadi-Pooya, Bauer, Fong, Haut, Haut, Haut, Haut, Herzog, Spencer, Sperling, Tonini, Woolley   +12 more
core   +2 more sources

The Association Between STX1B Polymorphisms and Treatment Response in Patients With Epilepsy

Frontiers in Pharmacology, 2021
Background: Epilepsy is a debilitating brain disease with complex inheritance and frequent treatment resistance. However, the role of STX1B single nucleotide polymorphisms (SNPs) in epilepsy treatment remains unknown.Objective: This study aimed to ...
Shitao Wang, Liang Zhou, Chenglu He, Dan Wang, Xuemei Cai, Yanying Yu, Liling Chen, Di Lu, Ligong Bian, Sunbing Du, Qian Wu, Yanbing Han   +11 more
doaj   +1 more source

Cannabis use patterns in drug-resistant and pharmacoresponsive epilepsy: Single tertiary referral center survey investigation.

PLoS ONE, 2023
This study sought to identify differences in cannabis use and perceptions about cannabis in mitigating seizure-related symptoms in patients with epilepsy, and to evaluate differences in these patterns between drug-resistant versus pharmacoresponsive ...
Danielle McDermott, Marielle L Darwin, Kirsten Fetrow, Ian Coulter, Kristal Biesecker, John A Thompson   +5 more
doaj   +1 more source

The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children [PDF]

, 2013
One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters.
Adnan Yuksel, Bahadir Batar, Gozde Yesil, Mehmet Guven, Mehmet Seven, Selin Unal   +5 more
core   +1 more source