Results 21 to 30 of about 33,337 (262)
Surgical Management for drug-resistant Epilepsy in Medial Temporal Lobe Lesions (Al-Azhar experience) [PDF]
Al-Azhar International Medical Journal, 2022 Background: The most common cause of drug resistant epilepsy is the temporal lobe seizures especially that caused by medial temporal lobe epileptogenic lesions.
alaa ibrahim, mohamed rashad
doaj +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Pathogenesis of drug resistant epilepsy
Эпилепсия и пароксизмальные состояния, 2019 Pharmacotherapy is the first-line treatment modality for epilepsy. However, in 20-40% of patients, epilepsy is resistant to pharmacotherapy. These numbers have not changed for decades despite the development and use of antiepileptic drugs with novel ...
S. M. Malyshev +3 more
doaj +1 more source
Drug Resistant Epilepsy Among Patients Attended The Neurosciences Hospital
مجله كليه طب الكندي, 2019 Background: Drug resistant epilepsy is defined as failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules to achieve sustained seizure freedom. Up to 30% of patients referred to clinics with a diagnosis of
Nael Husain Zaer
doaj +1 more source
Surgery in Epilepsy – How Advances in Human Neurology Can Benefit Veterinary Patients
Veterinary Evidence, 2016 This article reports the evidence behind pre-surgical evaluation and epilepsy surgery in human patients with drug-resistant idiopathic epilepsy and how this could potentially form the basis for the treatment of canine drug-resistant epilepsy in the ...
Marios Charalambous
doaj +1 more source
Frontiers in Pharmacology, 2021 One-third of patients with epilepsy suffer from drug-resistant epilepsy (DRE). Valproic acid (VPA) is a classic anticonvulsant drug, and its resistance is a crucial predictor of DRE, but the pathogenesis remain unknown.
Meng Fu +7 more
doaj +1 more source
Stress regulation in drug-resistant epilepsy [PDF]
Epilepsy & Behavior, 2017 The prevalence of psychological distress, especially depressive and anxiety disorders, is higher in epilepsy than in other chronic health conditions. These comorbid conditions contribute even more than epileptic seizures themselves to impaired quality of life in patients with epilepsy (PWE).
Kotwas, Iliana +4 more
openaire +4 more sources
EXPLORING COGNITIVE IMPAIRMENTS IN DRUG-RESISTANT EPILEPSY: INSIGHTS FROM A COMPARATIVE ANALYSIS
Journal of Social SciencesThis article explores the cognitive impairments in individuals with drug-resistant epilepsy compared to those with well-controlled epilepsy. The research involves 102 subjects (62 with drug-resistant epilepsy and 40 with well-controlled epilepsy), and ...
DOTEN, Natalia
doaj +1 more source
Frontiers in NeurologyAn increasing number of gene mutations associated with epilepsy have been identified, some linked to gray matter heterotopia—a common cause of drug-resistant epilepsy.
Zijian Li +5 more
doaj +1 more source
Evaluation of Risk Factors for Epilepsy in Pediatric Patients with Cerebral Palsy
Brain Sciences, 2020 Cerebral palsy (CP) is a set of etiologically diverse symptoms that change with the child’s age. It is one of the most frequent causes of motor disability in children. CP occurs at a frequency of 1.5 to 3.0 per 1000 live-born children.
Małgorzata Sadowska +2 more
doaj +1 more source