Results 21 to 30 of about 2,582,050 (300)
How do children with drug-resistant epilepsy sleep? A clinical and video-PSG study
, 2021 Aim: The aim of this study was to assess sleep architecture and sleep problems among three homogenous groups of children including children with drug-resistant focal epilepsy, children with newly diagnosed, drug-naive focal epilepsy, and healthy children
Arhan, Ebru +4 more
core +1 more source
The Association Between STX1B Polymorphisms and Treatment Response in Patients With Epilepsy
Frontiers in Pharmacology, 2021 Background: Epilepsy is a debilitating brain disease with complex inheritance and frequent treatment resistance. However, the role of STX1B single nucleotide polymorphisms (SNPs) in epilepsy treatment remains unknown.Objective: This study aimed to ...
Shitao Wang +11 more
doaj +1 more source
Assessment of clinical risk factors for drug-resistant epilepsy in children and teenagers [PDF]
, 2014 Introduction: Epilepsy is one of the most common neurological illnesses occurring in children. In approximately 20–30% of cases it is drug-resistant.
Janusz Wendorff +2 more
core +1 more source
PLoS ONE, 2023 This study sought to identify differences in cannabis use and perceptions about cannabis in mitigating seizure-related symptoms in patients with epilepsy, and to evaluate differences in these patterns between drug-resistant versus pharmacoresponsive ...
Danielle McDermott +5 more
doaj +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Pathophysiology of drug-resistant canine epilepsy
The Veterinary Journal, 2023 Drug resistance continues to be a major clinical problem in the therapeutic management of canine epilepsies with substantial implications for quality of life and survival times. Experimental and clinical data from human medicine provided evidence for relevant contributions of intrinsic severity of the disease as well as alterations in pharmacokinetics ...
Heidrun, Potschka +3 more
openaire +2 more sources
Revisiting the concept of drug-resistant epilepsy: A TASK1 report of the ILAE/AES Joint Translational Task Force [PDF]
, 2023 Despite progress in the development of anti-seizure medications (ASMs), one third of people with epilepsy have drug-resistant epilepsy (DRE). The working definition of DRE, proposed by the International League Against Epilepsy (ILAE) in 2010, helped ...
Galanopoulou, Aristea S +6 more
core +1 more source
Epilepsia Open, 2023 Objective For people with drug‐resistant epilepsy, the use of epilepsy surgery is low despite favorable odds of seizure freedom. To better understand surgery utilization, we explored factors associated with inpatient long‐term EEG monitoring (LTM), the ...
Chloe E. Hill +6 more
doaj +1 more source
Profile of once-daily zonisamide as monotherapy for treatment of partial seizures in adults [PDF]
, 2013 Marco MulaDivision of Neurology, Trinity Hospital, Borgomanero, ItalyAbstract: Epilepsy is one of the most common neurologic disorders, affecting about 50 million people around the world.
Mula M, Mula, M
core +1 more source
, 2021 Background: Cardiac problems have been suggested as causes of sudden unexpected death in epilepsy (SUDEP). Our aim was to investigate possible associations of cardiac autonomic functions based on heart rate variability (HRV) parameters with risk factors ...
Serbest, Nail Guven +8 more
core +1 more source