Results 251 to 260 of about 3,249,050 (351)

Communication regarding sudden unexpected death in epilepsy to people with epilepsy and their caregivers: A scoping review from the ILAE Sudden Unexpected Death in Epilepsy Task Force

open access: yesEpilepsia, EarlyView.
Abstract Discussing sudden unexpected death in epilepsy (SUDEP) is difficult and sensitive for health care providers (HCPs), people with epilepsy (PwE), and caregivers. This scoping review examines the literature on SUDEP communication, focusing on need, timing, content, methods, facilitators, barriers, and outcomes. We performed a thematic analysis to
Amir Aschner   +5 more
wiley   +1 more source

Impact of anterior callosal disconnection on picture naming in frontal lobe epilepsy surgery. [PDF]

open access: yesBrain Commun
Giampiccolo D   +12 more
europepmc   +1 more source

Fast cycle of vagus nerve stimulation is associated with increased sleep‐related breathing disorder in patients with epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective This work was undertaken to study the association between vagus nerve stimulation (VNS) parameters and the apnea–hypopnea index (AHI) measured by polysomnography in patients with drug‐resistant epilepsy. Methods Patients with epilepsy who underwent polysomnography with an active VNS device between 2018 and 2023 were retrospectively ...
Jacques‐François Massa   +8 more
wiley   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing   +4 more
wiley   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

Long-term survival after adult epilepsy surgery: Mortality and predictors in a large cohort. [PDF]

open access: yesEpilepsia
Fiore G   +6 more
europepmc   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng   +11 more
wiley   +1 more source

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