Results 1 to 10 of about 8,267 (258)

Different pharmacoresistance of focal epileptic spasms, generalized epileptic spasms, and generalized epileptic spasms combined with focal seizures [PDF]

Epilepsia Open, 2022
Objective Among standard treatments for infantile spasms, adrenocorticotropic hormone (ACTH) is reported as the best treatment, but ACTH is ineffective in one‐half of the patients.
Yukitoshi Takahashi, Akiko Ota, Jun Tohyama, Tomoko Kirino, Yumi Fujiwara, Chizuru Ikeda, Shigeki Tanaka, Jyunya Takahashi, Toshihiko Shinoki, Hiroshi Shiraga, Takushi Inoue, Hiroshi Fujita, Motoki Bonno, Masayoshi Nagao, Hideo Kaneko   +14 more
doaj   +7 more sources

Electroclinical Features of Infantile Epileptic Spasms Syndrome [PDF]

Annals of Indian Academy of Neurology
Epileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
doaj   +4 more sources

Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]

Frontiers in Pediatrics
IntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Linghui Zhu, Linghui Zhu, Yuan Xia, Yuan Xia, Hao Ding, Tong Zhang, Jun Li, Baomin Li, Baomin Li   +8 more
doaj   +3 more sources

Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]

Frontiers in Pediatrics
BackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen, Henry Chen, Adam L. Numis, Adam L. Numis, Renée A. Shellhaas, John R. Mytinger, Debopam Samanta, Rani K. Singh, Rani K. Singh, Shaun A. Hussain, Danielle Takacs, Kelly G. Knupp, Li-Rong Shao, Carl E. Stafstrom   +13 more
doaj   +3 more sources

EEG‐based spatiotemporal dynamics of fast ripple networks and hubs in infantile epileptic spasms [PDF]

Epilepsia Open, 2023
Objective Infantile epileptic spasms (IS) are epileptic seizures that are associated with increased risk for developmental impairments, adult epilepsies, and mortality.
Ioana M. A. Samfira, Aristea S. Galanopoulou, Hiroki Nariai, Jonathan M. Gursky, Solomon L. Moshé, Berj L. Bardakjian   +5 more
doaj   +4 more sources

Landscape of genetic infantile epileptic spasms syndrome—A multicenter cohort of 124 children from India [PDF]

Epilepsia Open, 2023
Objective Literature on the genotypic spectrum of Infantile Epileptic Spasms Syndrome (IESS) in children is scarce in developing countries. This multicentre collaboration evaluated the genotypic and phenotypic landscape of genetic IESS in Indian children.
Balamurugan Nagarajan, Vykuntaraju K. Gowda, Sangeetha Yoganathan, Indar Kumar Sharawat, Kavita Srivastava, Nitish Vora, Rahul Badheka, Sumita Danda, Umesh Kalane, Anupriya Kaur, Priyanka Madaan, Sanjiv Mehta, Sandeep Negi, Prateek Kumar Panda, Surekha Rajadhyaksha, Arushi Gahlot Saini, Lokesh Saini, Siddharth Shah, Varunvenkat M. Srinivasan, Renu Suthar, Maya Thomas, Sameer Vyas, Naveen Sankhyan, Jitendra Kumar Sahu   +23 more
doaj   +4 more sources

ACTH Therapy in Epileptic Spasms without Hypsarrhythmia

Pediatric Neurology Briefs, 2005
The short and long-term effects of adrenocorticotrophic hormone (ACTH) in 30 children ages 11 to 86 months (median 29 months) with epileptic spasms (ES) without hypsarrhythmia were analyzed at Tokyo Women’s Medical University, Japan.
J Gordon Millichap
doaj   +5 more sources

First‐choice hormonal therapies for children with infantile epileptic spasms syndrome in South Asia: A network meta‐analysis of randomized controlled trials [PDF]

Epilepsia Open
Considering the peculiar challenges with infantile epileptic spasms syndrome (IESS) in South Asia and a wide variation in the usage of hormonal therapies, we compared the efficacy and safety of various hormonal therapies for children with IESS in South ...
Nagita Devi, Priyanka Madaan, Nidhun Kandoth, Parth Lal, Jitendra Kumar Sahu, Dipika Bansal   +5 more
doaj   +3 more sources

Status Epilepticus Manifested as Continuous Epileptic Spasms [PDF]

Frontiers in Neurology, 2020
Objective: The etiology and outcome of status epilepticus with continuous epileptic spasms have not been fully understood; and only rare cases have been reported in the literature.
Jianxiang Liao, Tieshuan Huang, Myriam Srour, Yuhan Xiao, Yan Chen, Sufang Lin, Li Chen, Yan Hu, Lina Men, Jialun Wen, Bing Li, Feiqiu Wen, Lan Xiong   +12 more
doaj   +3 more sources

Infantile Spasms in Remission May Reemerge as Intractable Epileptic Spasms [PDF]

Epilepsia, 2003
Summary: Background:West syndrome consists of infantile spasms with hypsarrhythmia and is perceived as a disorder of infants.Methods:We describe 10 patients with West syndrome with spasms that remitted, started again, and persisted (followed up for 8–25 years).Results:In all, West syndrome developed at younger than 17 months (five cryptogenic, six ...
Peter Camfield, Carol Camfield, Anne Lortie, Husam Darwish   +3 more
openalex   +4 more sources