Results 21 to 30 of about 146,603 (292)

Early life seizures and epileptic spasms in STXBP1-related disorders. [PDF]

Epilepsia, 2023
Individuals with disease‐causing variants in STXBP1 frequently have epilepsy onset in the first year of life with a variety of seizure types, including epileptic spasms.
Thalwitzer KM, Xian J, de Campo D, Parthasarathy S, Magielski J, Sullivan KR, Goss J, Rigby CS, Boland M, Prosser B, Ruggiero SM, Syrbe S, Helbig I.   +12 more
europepmc   +2 more sources

Epileptic Spasms and Partial Seizures Associated with Vitamin B12 Deficiency: Case Report and Literature Review

Archives of Epilepsy, 2017
Epileptic spasms associated with vitamin B12 deficiency are rare. Epileptic spasms in addition to partial seizures due to vitamin B12 deficiency have never been reported in the literature. A 3½-month-old girl presented to clinic with partial seizures and
Uğur IŞIK, Sonay BEYATLI
doaj   +2 more sources

Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]

Frontiers in Pediatrics
IntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Linghui Zhu, Linghui Zhu, Yuan Xia, Yuan Xia, Hao Ding, Tong Zhang, Jun Li, Baomin Li, Baomin Li   +8 more
doaj   +2 more sources

A Multicenter Training and Interrater Reliability Study of the BASED Score for Infantile Epileptic Spasms Syndrome. [PDF]

J Clin Neurophysiol
Purpose: The best possible outcomes in infantile epileptic spasms syndrome require electroclinical remission; however, determining electrographic remission is not straightforward.
Mytinger JR, Albert DVF, Aylward SC, Beatty CW, Bhalla S, Bhatia S, Brock GN, Ciliberto MA, Choudhari PR, Clark DJ, Cohen JM, Czech TM, Fredwall MM, Gonzalez-Giraldo E, Harini C, Hunter SE, Sandoval Karamian AG, Katyayan A, Kistler I, Kulkarni N, Liu VB, McCabe C, Murray T, Neville K, Patel SH, Pavuluri S, Phillips DJ, Samanta D, Sirsi D, Spelbrink EM, Stafstrom CE, Steenari M, Takacs DS, Terrill T, Tran L, Vidaurre J, Shrey DW.   +36 more
europepmc   +2 more sources

Outcomes following resective and disconnective strategies in the treatment of epileptic spasms: a systematic review of the literature and individual patient data meta-analysis. [PDF]

Front Neurol
Epileptic spasms (ES) are a unique seizure type typically presenting in the form of infantile epileptic spasms syndrome (IESS) with characteristic hypsarrhythmia on scalp EEG and a preponderance with developmental delay or regression.
Cottier R, Niazi F, Goël K, Korman C, Porte T, Ducruet T, Cossu G, Briscoe C, Singh A, Harini C, Ibrahim GM, Fallah A, Weil AG, Hadjinicolaou A.   +13 more
europepmc   +2 more sources

Biomimetic Deep Learning Networks With Applications to Epileptic Spasms and Seizure Prediction. [PDF]

IEEE Trans Biomed Eng, 2023
Objective: In this study, we present a novel biomimetic deep learning network for epileptic spasms and seizure prediction and compare its performance with state-of-the-art conventional machine learning models.
Lucasius C, Grigorovsky V, Nariai H, Galanopoulou AS, Gursky J, Moshe SL, Bardakjian BL.   +6 more
europepmc   +2 more sources

Epileptic spasms in CDKL5 deficiency disorder: Delayed treatment and poor response to first‐line therapies [PDF]

Epilepsia, 2023
We aimed to assess the treatment response of infantile‐onset epileptic spasms (ES) in CDKL5 deficiency disorder (CDD) vs other etiologies.
Heather E. Olson, Scott Demarest, Elia Pestana‐Knight, Ahsan N. Moosa, Xiaoming Zhang, José R. Pérez‐Pérez, Judy Weisenberg, Erin O’Connor Prange, Eric D. Marsh, Rajsekar R. Rajaraman, Bernhard Suter, Akshat Katyayan, Isabel Haviland, Carolyn I. Daniels, Bo Zhang, Caitlin Greene, Michelle DeLeo, Lindsay C. Swanson, Jamie Love‐Nichols, Tim A. Benke, Chellamani Harini, Annapurna Poduri   +21 more
openalex   +2 more sources

Risk of autism spectrum disorder in children with infantile epileptic spasms syndrome: a retrospective study in a single center in Brazil [PDF]

Jornal de Pediatria
Objective: This study aimed to investigate the prevalence of autism spectrum disorder and its possible correlations with clinical characteristics in patients with infantile epileptic spasms syndrome in a single center in Brazil.
Marília Barbosa de Matos, Paulo Breno Noronha Liberalesso, Tiago dos Santos Bara, Paula Carolina Martins Alves Gomes, Bianca Simone Zeigelboim, Jair Mendes Marques, Mara L. Cordeiro   +6 more
doaj   +2 more sources

IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution

Neurotherapeutics
Little is known about the mechanisms that generate epileptic spasms following perinatal brain injury. Recent studies have implicated reduced levels of Insulin-like Growth Factor 1 (IGF-1) in these patients’ brains.
Carlos J. Ballester-Rosado, John T. Le, Trang T. Lam, Anne E. Anderson, James D. Frost, Jr., John W. Swann   +5 more
doaj   +2 more sources

Infantile epileptic spasms syndrome: a cohort study of 88 children. [PDF]

Ital J Pediatr, 2023
Ren LH, Zhang J, Li SX, Liu P, Chen H, Hu W.   +5 more
europepmc   +3 more sources