Results 41 to 50 of about 8,267 (258)

Unilobar surgery for symptomatic epileptic spasms

Annals of Clinical and Translational Neurology, 2016
AbstractObjectiveTo assess factors associated with favorable seizure outcome after surgery for symptomatic epileptic spasms and improve knowledge on pathophysiology of this seizure type.MethodsInclusion criteria were: (1) age between 6 months and 15 years at surgery; (2) active epileptic spasms; (3) follow‐up after surgery >1 year.ResultsWe ...
Barba, Carmen, Mai, Roberto, Grisotto, Laura, Gozzo, Francesca, Pellacani, Simona, Tassi, Laura, Francione, Stefano, Giordano, Flavio, Cardinale, Francesco, GUERRINI, RENZO   +9 more
openaire   +4 more sources

Epileptic spasms as the presenting seizure type in a patient with a new “O” of TORCH, congenital Zika virus infection

Epilepsy and Behavior Case Reports, 2019
Congenital TORCH infections are a significant cause of epileptic spasms, an infantile epileptic encephalopathy, through disruptions to several pathways in neurodevelopment. Congenital Zika virus has a similar neurotropism to other TORCH agents, and leads
Jason Lockrow, Hannah Tully, Russell P. Saneto   +2 more
doaj   +1 more source

A conundrum of West syndrome, behavioural problems and parental expressed emotions: a case report

General Psychiatry, 2020
West syndrome (WS) is the most common epileptic syndrome in infancy characterised by epileptic spasms, hypsarrhythmia and neurodevelopmental problems. Epileptic spasms remain in many ways a conundrum, and the ideal intervention, as well as how to screen ...
Yogender Kumar Malik, Nidhi Chauhan, Akhilesh Sharma, Susanta Padhy   +3 more
doaj   +1 more source

Short-term outcome of intravenous methylprednisolone pulse therapy versus oral prednisolone in patients with epileptic spasms

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Background Infantile spasm (IS) is an age-specific epileptic disorder of early infancy that typically presents with epileptic spasms occurring in clusters.
Abdelsattar Abdullah Elsayeh, Mohammad Ali Saeed Hassan   +1 more
doaj   +1 more source

Infantile epileptic spasms syndrome in a child with lissencephaly associated with de novo PAFAH1B1 variant and coincidental CMV infection. [PDF]

Epilepsy Behav Rep
Ying Eng N, Nie DA.
europepmc   +2 more sources

Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants

Arquivos de Neuro-Psiquiatria, 2023
Background Infantile epileptic spasms syndrome (IESS) is a rare but severe condition affecting children early and is usually secondary to an identifiable brain disorder.
Letícia Pereira de Brito Sampaio, Adélia Maria de Miranda Henriques-Souza, Mariana Ribeiro Marcondes da Silveira, Lisiane Seguti, Mara Lúcia Schmitz Ferreira Santos, Maria Augusta Montenegro, Sérgio Antoniuk, Maria Luíza Giraldes de Manreza   +7 more
doaj   +1 more source

Increased propensity for infantile spasms and altered neocortical excitation-inhibition balance in a mouse model of down syndrome carrying human chromosome 21

Neurobiology of Disease, 2023
Children with Down syndrome (DS, trisomy of chromosome 21) have an increased risk of infantile spasms (IS). As an epileptic encephalopathy, IS may further impair cognitive function and exacerbate neurodevelopmental delays already present in children with
Li-Rong Shao, Feng Gao, Viveka Chinnasamy, Yasuhiro Kazuki, Mistuo Oshimura, Roger H. Reeves, Carl E. Stafstrom   +6 more
doaj   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
openalex   +2 more sources

Treatment of Symptomatic Infantile Spasms

Pediatric Neurology Briefs, 2013
Investigators at Tokyo Women's Medical University studied the clinical, radiological, and EEG characteristics of 69 patients with infantile spasms (IS) followed for 3-74 months (mean 18 months) after initial cessation of epileptic spasms (ES).
J Gordon Millichap
doaj   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu Mowrey, Wei Liu, Anna‐Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
openalex   +2 more sources