Results 51 to 60 of about 12,577 (248)

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source

Getting the best outcomes from epilepsy surgery. [PDF]

, 2018
Neurosurgery is an underutilized treatment that can potentially cure drug-refractory epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to ensure optimal outcomes.
Duncan, John S, Elger, Christian E, Engel, Jerome, Staba, Richard, Vakharia, Vejay N, Witt, Juri-Alexander   +5 more
core  

Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]

, 2010
High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman, Finnerty, Gerald T, Jefferys, John G R, Jiruska, Premysl, Lofti, Noosheen, Powell, Andrew D   +5 more
core   +3 more sources

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Pathological high frequency oscillations associate with increased GABA synaptic activity in pediatric epilepsy surgery patients

Neurobiology of Disease, 2020
Pathological high-frequency oscillations (HFOs), specifically fast ripples (FRs, >250 Hz), are pathognomonic of an active epileptogenic zone. However, the origin of FRs remains unknown.
Carlos Cepeda, Simon Levinson, Hiroki Nariai, Vannah-Wila Yazon, Conny Tran, Joshua Barry, Katerina D. Oikonomou, Harry V. Vinters, Aria Fallah, Gary W. Mathern, Joyce Y. Wu   +10 more
doaj   +1 more source

Orbitofrontal epilepsy: Electroclinical analysis of surgical cases and literature review [PDF]

, 2004
Clinical and electrographic data were reviewed on 2 of our patients with orbitofrontal epilepsy who were seizure free at 5-year follow-up, and on 2 similar patients from the literature.
King, Don W., Loring, David W., Sillay, Karl, Smith, Joseph R., Winkler, Peter   +4 more
core   +1 more source

Permutation entropy‐derived parameters to estimate the epileptogenic zone network

Epilepsia, 2023
AbstractObjectiveQuantification of the epileptogenic zone network (EZN) most frequently implies analysis of seizure onset. However, important information can also be obtained from the postictal period, characterized by prominent changes in the EZN.
Bratu, Ionuț‐Flavius, Makhalova, Julia, Garnier, Elodie, Villalon, Samuel Medina, Jegou, Aude, Bonini, Francesca, Lagarde, Stanislas, Pizzo, Francesca, Trébuchon, Agnès, Scavarda, Didier, Carron, Romain, Bénar, Christian, Bartolomei, Fabrice   +12 more
openaire   +3 more sources

Functional Segregation of Epileptogenicity within the Human Amygdala

Annals of Neurology, EarlyView.
Objective In temporal lobe epilepsy (TLE), the amygdala in the epileptogenic network is underestimated compared to other regions such as the hippocampus. Recent advances in anatomical neuroimaging and stereoelectroencephalography (SEEG) signal analyses could help better understand the involvement of the different amygdala nuclei in the genesis of ...
Odile Feys, Julia Makhalova, Samuel Medina Villalon, Maria Fratello, Hugo Dary, Stanislas Lagarde, Francesca Pizzo, Agnès Trébuchon, Maxime Guye, Jean‐Philippe Ranjeva, Romain Carron, Didier Scavarda, Christian‐George Bénar, Bernard Giusiano, Fabrice Bartolomei   +14 more
wiley   +1 more source

Treatment and Outcome of Epileptogenic Temporal Cavernous Malformations

Chinese Medical Journal, 2015
Background: The aim of this study is to explore the treatment and outcome of epileptogenic temporal lobe cavernous malformations (CMs). Methods: We analyzed retrospectively the profiles of 52 patients diagnosed as temporal lobe CMs associated with ...
Yong-Zhi Shan, Xiao-Tong Fan, Liang Meng, Yang An, Jian-Kun Xu, Guo-Guang Zhao   +5 more
doaj   +1 more source

Influence of metallic artifact filtering on MEG signals for source localization during interictal epileptiform activity [PDF]

, 2016
Objective. Medical intractable epilepsy is a common condition that affects 40% of epileptic patients that generally have to undergo resective surgery.
Alonso López, Joan Francesc, Mañanas Villanueva, Miguel Ángel, Migliorelli Falcone, Carolina Mercedes, Nowak, Rafal, Romero Lafuente, Sergio, Russi Tintoré, Antonio   +5 more
core   +2 more sources