Results 71 to 80 of about 12,577 (248)

Tuberous Sclerosis and Multiple Tubers: Localizing the Epileptogenic Zone [PDF]

Epilepsia, 2004
Summary:  Tuberous sclerosis complex (TSC) is associated with medically refractory seizures and developmental delay in children. These epilepsies are often resistant to antiepileptic drugs (AEDs), may be quite severe, and usually have a negative impact on the child's neurological and cognitive development.
openaire   +2 more sources

Delayed brain and spine migration of a retained SEEG electrode fragment: An unexpected complication

Epileptic Disorders, EarlyView.
Abstract Background Stereoelectroencephalography (SEEG) is a well‐established technique for localizing epileptogenic zones in patients with drug‐resistant epilepsy, including children. While considered safe, rare but serious complications can occur.
Manel Krouma, Julia Makhalova, Gauthier Toutain, Francesca Pizzo, Stanislas Lagarde, Anne Lepine, Fabrice Bartolomei, Didier Scavarda   +7 more
wiley   +1 more source

Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research

Indian Journal of Neurosurgery, 2013
Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons ...
Jyotirmoy Banerjee, Manjari Tripathi, P. Sarat Chandra   +2 more
doaj   +1 more source

Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2. [PDF]

PLoS ONE, 2015
Synapsins are pre-synaptic vesicle-associated proteins linked to the pathogenesis of epilepsy through genetic association studies in humans. Deletion of synapsins causes an excitatory/inhibitory imbalance, exemplified by the epileptic phenotype of ...
Deepti Chugh, Idrish Ali, Anahita Bakochi, Elma Bahonjic, Lars Etholm, Christine T Ekdahl   +5 more
doaj   +1 more source

Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options. [PDF]

, 2014
Seizures are clinically significant manifestations associated with 79%-90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and ...
Fallah, Aria, Wang, Shelly
core   +2 more sources

Bilateral ictal eye closure in focal epileptic seizures: SEEG retrospective observational assessment from a tertiary epilepsy center

Epileptic Disorders, EarlyView.
Abstract Ictal eye closure is commonly associated with functional seizures but may also occur in epileptic seizures. We retrospectively reviewed 113 consecutive stereo‐EEG (SEEG) recordings from adults with drug‐resistant focal epilepsy (2015–2024) to identify prolonged bilateral eye closure during seizures.
Paola Vassallo, Christina Pourlou, Joana F. A. Oliveira, Davide Giampiccolo, Charlotte McLaughlin, Emma Torzillo, Umair Javaid Chaudhary, John S. Duncan, Josemir W. Sander, Fahmida Chowdhury, Beate Diehl   +10 more
wiley   +1 more source

Seizure-onset mapping based on time-variant multivariate functional connectivity analysis of high-dimensional intracranial EEG : a Kalman filter approach [PDF]

, 2016
The visual interpretation of intracranial EEG (iEEG) is the standard method used in complex epilepsy surgery cases to map the regions of seizure onset targeted for resection.
Lie, Octavian V, van Mierlo, Pieter
core   +1 more source

Learning to define an electrical biomarker of the epileptogenic zone [PDF]

Human Brain Mapping, 2019
AbstractThe role of fast activity as a potential biomarker in localization of the epileptogenic zone (EZ) remains controversial due to recently reported unsatisfactory performance. We recently identified a “fingerprint” of the EZ as a time‐frequency pattern that is defined by a combination of preictal spike(s), fast oscillatory activity, and concurrent
Jian Li, Olesya Grinenko, John C. Mosher, Jorge Gonzalez‐Martinez, Richard M. Leahy, Patrick Chauvel   +5 more
openaire   +2 more sources

Ictal semiology in fronto‐opercular epilepsy: A systematic review

Epileptic Disorders, EarlyView.
Abstract A systematic review of the ictal semiology of fronto‐opercular seizures in focal epilepsy was carried out to assess possible anatomical‐clinical correlations and help guide interpretation of ictal semiology during pre‐surgical evaluation. PubMed and Embase databases were searched using the following keywords: “fronto‐opercular OR frontal ...
Zeynep Gokce‐Samar, Alexandra Montavont, Marion Comajuan, Julitta de Bellescize, Eleni Panagiotakaki, Marietta Papadopoulou, Matthildi‐Athina Papathanasiou‐Terzi, Joseph Toulouse, Alexis Arzimanoglou, Karine Ostrowsky‐Coste   +9 more
wiley   +1 more source

Automated long‐term EEG analysis to localize the epileptogenic zone

Epilepsia Open, 2017
SummaryObjectiveWe investigated the performance of automatic spike detection and subsequent electroencephalogram (EEG) source imaging to localize the epileptogenic zone (EZ) from long‐term EEG recorded during video‐EEG monitoring.MethodsIn 32 patients, spikes were automatically detected in the EEG and clustered according to their morphology.
Van Mierlo, Pieter, Strobbe, Gregor, Keereman, Vincent, Birot, Gwénaël, Gadeyne, Stefanie, Gschwind, Markus, Carrette, Evelien, Meurs, Alfred, Van Roost, Dirk, Vonck, Kristl, Seeck, Margitta, Vulliemoz, Serge, Boon, Paul   +12 more
openaire   +5 more sources