Results 81 to 90 of about 12,577 (248)

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study

Epilepsia, EarlyView.
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng, Aswin Chari, Maria H. Eriksson, Freya Prentice, Xiaosong He, Hua Xie, Leigh Sepeta, M. Zubair Tahir, Jonathan D. Clayden, Martin M. Tisdall, Torsten Baldeweg, Rory J. Piper   +11 more
wiley   +1 more source

Epileptogenic networks and drug-resistant epilepsy: Present and future perspectives of epilepsy research-Utility for the epileptologist and the epilepsy surgeon

Annals of Indian Academy of Neurology, 2014
A multidisciplinary approach is required to understand the complex intricacies of drug-resistant epilepsy (DRE). A challenge that neurosurgeons across the world face is accurate localization of epileptogenic zone.
Jyotirmoy Banerjee, Sarat P Chandra, Nilesh Kurwale, Manjari Tripathi   +3 more
doaj   +1 more source

Localization of the Epileptogenic Foci in Tuberous Sclerosis Complex: A Pediatric Case Report [PDF]

, 2014
Tuberous sclerosis complex (TSC) is a rare disorder of tissue growth and differentiation, characterized by benign hamartomas in the brain and other organs.
Ahtam, Banu, Camposano, Susana, Doshi, Chiran, Grant, Patricia Ellen, Harini, Chellamani, Haueisen, Jens, Hunold, Alexander, Okada, Yoshio, Papadelis, Christos, Warfield, Simon K.   +9 more
core   +2 more sources

Biomarkers of epileptogenic zone defined by quantified stereo‐EEG analysis [PDF]

Epilepsia, 2014
SummaryObjectiveIn one third of patients with a diagnosis of pharmacoresistant focal epilepsy who are candidates for therapeutic surgery, cerebral areas responsible for seizure generation can be defined exclusively with invasive intracranial recordings. A correct presurgical identification of the epileptogenic zone (EZ) with intracranial electrodes has
Gnatkovsky V, de Curtis M, Pastori C, Cardinale F, Lo Russo G, Mai R, Nobili L, Sartori I, Tassi L, Francione S.   +9 more
openaire   +2 more sources

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

Epilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras, Birgit Frauscher, Jean Gotman, Julia Jacobs, Philippe Kahane, Richard J. Staba, Maeike Zijlmans   +6 more
wiley   +1 more source

Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy

npj Digital Medicine
Surgical success for patients with focal drug resistant epilepsy (DRE) relies on accurate localization of the epileptogenic zone (EZ). Currently, no exam delineates this zone unambiguously. Instead, the EZ is approximated by the area where seizures begin,
Hmayag Partamian, Saeed Jahromi, Ludovica Corona, M. Scott Perry, Eleonora Tamilia, Joseph R. Madsen, Jeffrey Bolton, Scellig S. D. Stone, Phillip L. Pearl, Christos Papadelis   +9 more
doaj   +1 more source

MP2RAGE vs. MPRAGE surface-based morphometry in focal epilepsy.

PLoS ONE
In drug-resistant focal epilepsy, detecting epileptogenic lesions using MRI poses a critical diagnostic challenge. Here, we assessed the utility of MP2RAGE-a T1-weighted sequence with self-bias correcting properties commonly utilized in ultra-high field ...
Cornelius Kronlage, Ev-Christin Heide, Gisela E Hagberg, Benjamin Bender, Klaus Scheffler, Pascal Martin, Niels Focke   +6 more
doaj   +1 more source

Deep characterization of refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) and insights into the role of invasive monitoring

Epilepsia, EarlyView.
Abstract Objective Epilepsy surgery is an effective treatment option for patients with medically refractory epilepsy due to mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE). The success of surgery depends on the accurate localization of the epileptogenic zone, which can be challenging due to the subtle imaging ...
Jean Khoury, Ingmar Blümcke, Robyn M. Busch, Balu Krishnan, Juan Bulacio, William Bingaman, Demitre Serletis, Imad Najm   +7 more
wiley   +1 more source

Gender, Psychiatric and Cognitive Status Related to Experiential Auras in Patients with Temporal Lobe Epilepsy [PDF]

, 2018
Objective: To determine whether the experiential auras in patients with temporal lobe epilepsy (TLE) are related to gender, psychiatric comorbidity, material-specific memory impairment, lateralization by video-EEG and structural neuroimaging ...
Benjumea Cuartas, Vanessa, Giagante, Brenda, Kochen, Sara Silvia   +2 more
core  

Inverse Modeling for MEG/EEG data

, 2017
We provide an overview of the state-of-the-art for mathematical methods that are used to reconstruct brain activity from neurophysiological data. After a brief introduction on the mathematics of the forward problem, we discuss standard and recently ...
A Doucet, A Galka, A Gramfort, A Pascarella, A Sorrentino, A Sorrentino, A Sorrentino, C Campi, C Lamus, CJ Long, D Calvetti, DK Nguyen, E Somersalo, F Cardinale, F Pasquale de, F-H Lin, G Dassios, GR Barnes, H Murakami, JC Mosher, JC Mosher, JM Antelis, JR Wolpaw, K Sekihara, K Uutela, K Uutela, L Miao, L Rabiner, M Hämäläinen, M Kowalski, MS Hämäläinen, PJ Green, R Bouet, RG Andrzejak, S Pursiainen, S Sommariva, SC Jun, TS Tian, V Vivaldi, W Ou, X Chen   +40 more
core   +1 more source