Results 111 to 120 of about 2,093,419 (291)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Episodic memory training with emphasis on categorization for older adults without dementia and depression / Treino de memória episódica com ênfase em categorização para idosos sem demência e depressão

Psicologia: Reflexão e Crítica, 2010
Aging may lead to cognitive changes, especially in memory. Yet, research suggests that older adults may improve memory performance after training. The present study aimed at evaluating the effects of episodic memory training offered to healthy Brazilian ...
Fabiana Castillo Roda Carvalho, Anita Liberalesso Neri, Mônica Sanches Yassuda   +2 more
doaj  

Neural correlates of episodic memory buildup in naturalistic viewing behavior [Elektronisk resurs]

, 2021
In everyday life, we bind visual samples of the world into a coherent episodic memory via eye movements. Previous eye tracking research revealed that visual scrutiny, gaze transitions between event elements, and refixations during encoding predict ...
Johansson, Roger,, Johansson, Mikael,, Lund University., Nikolaev, Andrey,, Bramao, Ines,   +4 more
core  

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Longitudinal functional connectivity during rest and task is differentially related to Alzheimer’s pathology and episodic memory in older adults

Scientific Reports
Changes in functional connectivity (FC) strength involving the medial temporal lobe (MTL) and posteromedial cortex (PMC) are related to early Alzheimer’s pathology and alterations in episodic memory performance in cognitively unimpaired older adults, but
Larissa Fischer, Jenna N. Adams, Eóin N. Molloy, Jennifer Tremblay-Mercier, Jordana Remz, Alexa Pichet Binette, M. Natasha Rajah, Sylvia Villeneuve, Anne Maass, PREVENT-AD Research Group   +9 more
doaj   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

Further development of an episodic-like task in rats. [PDF]

, 2008
This thesis aimed to study the impairment observed in rats with fornix damage when performing an episodic memory task that requires recall of the location of objects in a context.
Jiménez Rodríguez, Mónica
core  

How episodic and working memory affect rule- and memory-based judgments [PDF]

, 2013
Making accurate judgments is an essential skill in everyday life. However, little is known about the basic cognitive skills required for accurate judgments. Research on judgment and categorization processes suggests that people rely on various strategies
Rieskamp, Jörg, von Helversen, Bettina, Hoffmann, Janina A., Hoffmann, Janina A, Hoffmann, Janina Anna   +4 more
core   +1 more source

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

Advanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo, Xingxing Li, Chenjun Zou, Chao Zheng, Xiaohong Wu, Xuechao Lu, Jiaying Yan, Junfang Zhang, Xiaoyan Luo, Shiwei Ye, Dongsheng Zhou   +10 more
wiley   +1 more source

Interdependence of episodic and semantic memory: evidence from neuropsychology. [PDF]

, 2010
Tulving's (1972) theory of memory draws a distinction between general knowledge (semantic memory) and memory for events (episodic memory). Neuropsychological studies have generally examined each type of memory in isolation, but theorists have long ...
Daniel L Greenberg, Mieke Verfaellie, Memory Daniel L Greenberg   +2 more
core