Results 121 to 130 of about 138,819 (251)

P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]

open access: yes, 2002
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ   +11 more
core   +1 more source

Headache disorders among Indigenous communities: A scoping review undertaken with knowledge keeper guidance

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective We performed a scoping review of literature on headache etiology, classification, prevalence, and treatment in Indigenous communities in Canada, the United States, Australia, and New Zealand. Background In the United States, analysis of national prevalence indicates that Indigenous Americans lead all other racial/ethnic groups in ...
Maia Kelly   +6 more
wiley   +1 more source

Sleep patterns in episodic migraine without aura: a polysomnographic study [PDF]

open access: yesRomanian Journal of Neurology
Background and objectives. Sleep disturbances are frequently reported in patients with migraine; however, the specific alterations in sleep architecture associated with episodic migraine without aura remain insufficiently defined.
Ahmed Hamdy, Aya Zhran
doaj   +1 more source

Opioid use, disability, and patient‐reported cognitive impairment in migraine: Multi‐country results from the Chronic Migraine Epidemiology and Outcomes—International Study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Opioids are widely used to treat migraine despite being contrary to clinical guidelines. In the Chronic Migraine Epidemiology and Outcomes–International (CaMEO‐I) Study, a large, international survey of people with migraine, opioid users were more likely than nonusers to experience moderate or severe migraine‐related disability ...
Elizabeth Leroux   +10 more
wiley   +1 more source

Pregnancy outcomes following exposure to galcanezumab: Analysis of cases from the galcanezumab clinical trials and postmarketing database

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to describe pregnancy outcomes reported following maternal or paternal exposure to galcanezumab in clinical trials and postmarketing surveillance. Background Galcanezumab is a calcitonin gene‐related peptide‐inhibiting monoclonal antibody indicated for the preventive treatment of migraine.
Irene Boz   +8 more
wiley   +1 more source

Cognition, mental health, and quality of life in patients with chronic and episodic migraine during the interictal period

open access: yesBMC Neurology
Introduction Migraine is a highly prevalent and disabling condition, not only due to its painful symptoms but also because of its significant impact on mental health and cognitive functioning, leading to a considerable deterioration in quality of life ...
Diana Carolina López-Medina   +6 more
doaj   +1 more source

The MIND study: Design, feasibility, and baseline characteristics of a smartphone‐based migraine cohort

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Our objective was to describe the design, feasibility, and baseline characteristics of the Migraine Impact on Neurocognitive Dynamics study, a 30‐day smartphone‐based, prospective, decentralized, observational cohort study evaluating high‐frequency assessment of cognition and symptoms in adults with migraine.
Babak Khorsand   +3 more
wiley   +1 more source

Navigating migraine chronicity: the role of environmental risk factors and triggers

open access: yesFrontiers in Neurology
PurposeMigraine is a prevalent and debilitating neurological condition that can significantly impact an individual’s quality of life. While various genetic and environmental factors contribute to the development and chronification of migraine, the role ...
Hasan Doğan   +9 more
doaj   +1 more source

Longitudinal effects of CGRP‐targeting migraine therapies on blood pressure and body mass index: A 12‐month retrospective analysis

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To compare blood pressure (BP) and body mass index (BMI) trajectories associated with individual calcitonin gene‐related peptide (CGRP)‐targeting migraine therapies versus matched CGRP‐unexposed controls. Background CGRP is a potent vasodilator with established roles in vascular homeostasis and metabolic regulation.
Phillip Phan   +6 more
wiley   +1 more source

Real‐world diagnosis and treatment of individuals with migraine in the United States: The Migraine Insights in Diagnosis and Treatment (MIND) study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objective of this study was to describe the real‐world diagnosis and treatment patterns of individuals newly diagnosed with migraine in the United States (US). Background Over 10% of adults in the US are living with migraine.
Fred Cohen   +7 more
wiley   +1 more source

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