Results 121 to 130 of about 29,074 (248)
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Hereditary Hemorrhagic Telangiectasia (HHT) is a rare autosomal dominant bleeding disorder. The incidence of venous thromboembolisms among HHT patients is significantly greater than the general population. However, providing therapeutic anticoagulation in patients with an increased propensity for bleeding creates a clinical dilemma.
Christina Carfagnini, Manasa Kandula
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.(1) GPX3 inhibits VDAC1 oligomerisation by directly binding to it. (2) The loss of GPX3 leads to VDAC1 oligomerisation, resulting in dysregulation of mitochondrial quality control, characterised by enhanced fission, weakened fusion and impaired autophagy.
Yuechen Wang +12 more
wiley +1 more source
A building-block Royal Road where crossover is provably essential
, 2007 One of the most controversial yet enduring hypotheses about what genetic algorithms (GAs) are good for concerns the idea that GAs process building-blocks.
Richard A. Watson +3 more
core +1 more source
Engineering Reports, Volume 8, Issue 6, June 2026.This systematic review traces the evolution of protein function prediction from experimental methods through homology‐based tools, ML and DL to XAI. While deep learning models achieve state‐of‐the‐art predictive accuracy, their black‐box nature limits biological insight and clinical trust.
Aastha Katiyar, Rashmi Yadav
wiley +1 more source
The genetics of host adaptation in the parasitic plant Striga hermonthica [PDF]
, 2013 The obligately outbreeding root hemiparasite Striga hermonthica (Orobanchaceae)is a serious threat to subsistence agriculture in sub-Saharan Africa. Resistance to this parasite in its crop hosts, such as rice, sorghum and maize, is not common, and the ...
Pescott, Oliver
core
Reconstructing a metazoan genetic pathway with transcriptome-wide epistasis measurements
, 2018 Significance Transcriptome profiling quantitatively measures gene expression genome-wide. There is widespread interest in using transcriptomic profiles as phenotypes for epistasis analysis.
Barbara J. Wold +4 more
core +1 more source
General Psychiatry, Volume 39, Issue 3, June 2026.ABSTRACT Background Current research suggests that genetic risk for psychiatric disorders is largely due to distinct combinations of many common variants shared by different disorders. This points to the existence of latent components affecting different dimensions of psychopathology.
Fernando Facal +2 more
wiley +1 more source
Epistasis correlates to genomic complexity
, 2006 4 pages, 2 figures.-- Additional information (Suppl. Table S2: Synopsis of the studies seeking for epistasis between deleterious mutations, and Suppl. text: Possible factors that could have led to an artefactual correlation between epistasis and genome ...
Elena, Santiago F., Sanjuán, Rafael
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Modern Agriculture, Volume 4, Issue 1, June 2026.To address the GWAS data scarcity in Pyropia haitanensis, 280 double‐haploid strains were phenotyped for 11 agronomic traits. GWAS analysis identified 454 candidate genes clustered on chromosome 4. Two molecular markers were validated: RPN5 (C/G SNP at Chr4:4,319,644) for thallus length, and DWF1 (T/G SNP at Chr4:4,485,590) for maturity days ...
Yan Xu +7 more
wiley +1 more source
Evolutionary accessibility of mutational pathways
, 2011 Functional effects of different mutations are known to combine to the total effect in highly nontrivial ways. For the trait under evolutionary selection (‘fitness’), measured values over all possible combinations of a set of mutations yield a fitness ...
J Arjan G M de Visser +9 more
core +1 more source