Results 111 to 120 of about 29,074 (248)

The vesicle trafficking R‐SNARE VAMP714 connects auxin responses, ROS and ion homeostasis in Arabidopsis under salt stress

New Phytologist, Volume 251, Issue 1, Page 207-227, July 2026.
Network of VAMP714‐dependent interactions during salt stress. Summary Plant responses to salt stress include an altered root architecture mediated by ion imbalances, reactive oxygen species (ROS) accumulation, and altered hormonal responses. Auxin is implicated in these processes.
Jialei Sun, Julien Agneessens, Jennifer F. Topping, Keith Lindsey   +3 more
wiley   +1 more source

Epistasis: Searching for Interacting Genetic Variants Using Crosses [PDF]

G3 Genes|Genomes|Genetics, 2017
Within quantitative genetics, the term “epistasis” is used to broadly describe situations in which combinations of genetic variants show nonadditive phenotypic effects ([Phillips 1998][1], [2008][2]; [Mackay 2014][3]).
openaire   +4 more sources

Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies

BioData Mining, 2019
Background In Genome-Wide Association Studies (GWAS), the concept of linkage disequilibrium is important as it allows identifying genetic markers that tag the actual causal variants.
Marc Joiret, Jestinah M. Mahachie John, Elena S. Gusareva, Kristel Van Steen   +3 more
doaj   +1 more source

Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Indicine cattle display a broad range of coat colors, representing a relevant and breed‐defining trait required for registration in breeder association. Among the genes involved in pigmentation, MC1R stands out for modulating the synthesis of melanin‐related proteins and remains poorly explored in indicine cattle breeds. Therefore, we aimed to
Silel V. S. A. Maciel, Ingrid P. P. Oliveira, Beatriz B. Senes, Carolaine J. S. Santana, Jackeline S. Alves, Edilane A. da Silva, Fernando O. Franco, Bárbara C. F. da Silva, Fernando C. Cairo, Frederico C. Cairo, Aníbal E. Vercesi‐Filho, Raphael B. Costa, Gregório M. F. de Camargo   +12 more
wiley   +1 more source

Distinct network patterns emerge from Cartesian and XOR epistasis models: a comparative network science analysis

BioData Mining
Background Epistasis, the phenomenon where the effect of one gene (or variant) is masked or modified by one or more other genes, significantly contributes to the phenotypic variance of complex traits.
Zhendong Sha, Philip J. Freda, Priyanka Bhandary, Attri Ghosh, Nicholas Matsumoto, Jason H. Moore, Ting Hu   +6 more
doaj   +1 more source

ASIP Variants in Livestock: It's Not Black and White

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Fur and feather pigmentation play an important role in the survival and reproduction of many species, as well as in selective breeding and agriculture. The synthesis of pigment molecules, eumelanin and pheomelanin, is partially regulated by the agouti signalling protein (ASIP) encoded by the ASIP gene.
Isabella M. Brown, Kylie A. Munyard
wiley   +1 more source

Imputation of quantitative genetic interactions in epistatic MAPs by interaction propagation matrix completion [PDF]

, 2014
A popular large-scale gene interaction discovery platform is the Epistatic Miniarray Profile (E-MAP). E-MAPs benefit from quantitative output, which makes it possible to detect subtle interactions.
Marinka Žitnik, Zupan, Blaz, Blaž Zupan, Zitnik, Marinka   +3 more
core   +1 more source

Orthogonal Decomposition of the Genetic Variance for Epistatic Traits Under Linkage Disequilibrium—Applications to the Analysis of Bateson-Dobzhansky-Müller Incompatibilities and Sign Epistasis

Frontiers in Genetics, 2019
The one-century-old theory of orthogonal genetic variance decomposition originated the field of quantitative genetics and has kept on being improved ever since.
José M. Álvarez-Castro, Rosa M. Crujeiras   +1 more
doaj   +1 more source

Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) recently celebrated its 20th anniversary, reflecting two decades of major contributions to Alzheimer's research through open data sharing and longitudinal multimodal assessments. This review synthesizes 122 high‐impact studies using ADNI data or biospecimens from 2023 to mid‐2025 to ...
Dallas P. Veitch, Melanie J. Miller, Shaveta Kanoria, Paul S. Aisen, Laurel A. Beckett, Robert C. Green, Danielle J. Harvey, Clifford R. Jack Jr., William Jagust, Edward B. Lee, Kwangsik Nho, Rachel Nosheny, Ozioma C. Okonkwo, Richard J. Perrin, Ronald C. Petersen, Monica Rivera Mindt, Andrew J. Saykin, Leslie M. Shaw, Arthur W. Toga, Duygu Tosun, Susan M Landau, Michael W. Weiner, for the Alzheimer's Disease Neuroimaging Initiative   +22 more
wiley   +1 more source

Privacy-preserving decision tree for epistasis detection

Cybersecurity, 2019
The interaction between gene loci, namely epistasis, is a widespread biological genetic phenomenon. In genome-wide association studies(GWAS), epistasis detection of complex diseases is a major challenge. Although many approaches using statistics, machine
Qingfeng Chen, Xu Zhang, Ruchang Zhang
doaj   +1 more source