Results 91 to 100 of about 25,753 (217)

An extension of the Walsh-Hadamard transform to calculate and model epistasis in genetic landscapes of arbitrary shape and complexity.

PLoS Computational Biology
Accurate models describing the relationship between genotype and phenotype are necessary in order to understand and predict how mutations to biological sequences affect the fitness and evolution of living organisms.
Andre J Faure, Ben Lehner, Verónica Miró Pina, Claudia Serrano Colome, Donate Weghorn   +4 more
doaj   +1 more source

Translating Riedl: The Circulation and Operationalisation of Evolutionary Ideas

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Rupert Riedl's Order in Living Organisms proposed a systems theory of evolution decades before the concepts it pioneered—homology, burden, the imitative epigenotype—reached the agenda of evolutionary biology. This paper reconstructs the lineages that operationalized his insights across several fields and explores the internal and external reasons for ...
Laura Nuño de la Rosa
wiley   +1 more source

Widespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common Environment.

PLoS Biology, 2017
Independently evolving populations may adapt to similar selection pressures via different genetic changes. The interactions between such changes, such as in a hybrid individual, can inform us about what course adaptation may follow and allow us to ...
Jasmine Ono, Aleeza C Gerstein, Sarah P Otto   +2 more
doaj   +1 more source

Impact of plant breeding on the responsiveness of maize and wheat varieties to an arbuscular mycorrhizal fungal symbiont

PLANTS, PEOPLE, PLANET, EarlyView.
Field inoculation with arbuscular mycorrhizal fungi (AMF) offers a promising route to improve sustainable agriculture and food production, yet results are often variable. We investigated the mycorrhizal growth response of maize and wheat varieties recommended for farmers and found substantial variation under greenhouse conditions.
Ido Rog, Marco Malinowski, Dylan Baumann, Raphaël Boussageon, Stefanie Lutz, Marcel G. A. van der Heijden   +5 more
wiley   +1 more source

Genomic architecture and breeding trade‐offs of coconut drought tolerance

PLANTS, PEOPLE, PLANET, EarlyView.
The coconut palm is an extremely popular and economically important crop, with around 65 million tonnes produced in 2023. Although Africa's coconut sector is growing rapidly, it—and the livelihoods that depend on it—is threatened by climate change, particularly increased drought.
Theodore S. Brook, Tom Versluys, Bi Tra Serges Doubi, Sam Acors, Jahcub Trew, Kyle Macleod, Louis Bell‐Roberts, Katarina Piponi, Jean Louis Konan, Konan Engueran Djaha, Hala N'klo, Benjamin J. Roberts, Catherine M. Collins, Matteo Fumagalli, Julien Godwin, Vincent Savolainen   +15 more
wiley   +1 more source

Advancing FAIR phylogenetics for health threats: a systematic review of SARS‐CoV‐2 research and guidelines for future outbreaks

Cladistics, EarlyView.
Abstract During the COVID‐19 pandemic, the need for quick public health action often conflicted with the careful methods required in phylogenetics. To explore this, we reviewed 217 SARS‐CoV‐2 studies published from January 2020 to March 2025 in 121 journals.
Omkar Marne, Denis Jacob Machado
wiley   +1 more source

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

PLoS Genetics, 2008
Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which is the interaction between alleles at different loci. We propose a framework for estimating and interpreting epistasis from a classical experiment that
David L Aylor, Zhao-Bang Zeng
openaire   +4 more sources

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

Immunology, EarlyView.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang, Fengyu Liu, Yongle Wei, Guoqiang Li, Liujie Zheng, Lin Jin, Feng Luan, Yingze Zhang, Ling Wang, Zhiyong Hou   +9 more
wiley   +1 more source

Genetic Evaluation of Pure Line Laying Hens Based on Crossover Testing Data From Simulated Populations

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Commercial laying hen breeding programs aim to maximize the performance of crossbred animals. However, selection is usually based on data from pure lines raised in controlled nucleus environments, which may not fully predict the yields under commercial conditions.
M. Sánchez‐Diaz, N. Ibáñez‐Escriche, D. López‐Carbonell, D. Cavero, L. Varona   +4 more
wiley   +1 more source

Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower

New Phytologist, EarlyView.
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley   +1 more source