Results 81 to 90 of about 25,247 (211)

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower

New Phytologist, EarlyView.
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Yield heterosis has been extensively exploited in hybrid breeding, with intersubspecific hybrids often exhibiting the most pronounced effects. However, developing elite hybrids remains a laborious and time‐consuming process. The genetic basis of heterosis has been debated for over a century, hindered largely by the lack of high‐quality genomes.
Zhiwu Dan, Yunping Chen, Wenchao Huang
wiley   +1 more source

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

PLoS Genetics, 2008
Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which is the interaction between alleles at different loci. We propose a framework for estimating and interpreting epistasis from a classical experiment that
David L Aylor, Zhao-Bang Zeng
openaire   +4 more sources

A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber

Plant Biotechnology Journal, EarlyView.
ABSTRACT Trichomes, the hair‐like outgrowths of the plant epidermis, are critical for defence, reproduction and development. However, the underlying molecular mechanisms governing their initiation remain elusive. Here, we identified CsGL2, an AP2/ERF transcription factor, as a key integrator controlling trichome initiation and fruit development in ...
Haifan Wen, Hui Du, Siqi Wang, Yiqun Weng, Juan Liu, Huanle He, Run Cai, Jian Pan, Junsong Pan   +8 more
wiley   +1 more source

Haplotypes and Machine Learning Improve Genomic Prediction in Brassica napus

Plant Biotechnology Journal, EarlyView.
ABSTRACT Genomic selection (GS) is a crop and livestock improvement method suited for predicting complex agronomical traits, while genomic prediction (GP) is the development of GS models prior to their practical use in breeding programs. One of the challenges in GP is accounting for how complex genomic interactions, such as epistasis, affect the ...
Tessa R. MacNish, Hawlader A. Al‐Mamun, Thomas Bergmann, Lixi Jiang, David Edwards   +4 more
wiley   +1 more source

Epistasis: Searching for Interacting Genetic Variants Using Crosses [PDF]

G3 Genes|Genomes|Genetics, 2017
Within quantitative genetics, the term “epistasis” is used to broadly describe situations in which combinations of genetic variants show nonadditive phenotypic effects ([Phillips 1998][1], [2008][2]; [Mackay 2014][3]).
openaire   +4 more sources

Poor statistical power in population-based association study of gene interaction

BMC Medical Genomics
Background Statistical epistasis, or “gene–gene interaction” in genetic association studies, means the nonadditive effects between the polymorphic sites on two different genes affecting the same phenotype.
Jiarui Ma, Jian Li, Yuqi Chen, Zhen Yang, Yungang He   +4 more
doaj   +1 more source

The OsWRKY15‐OsSUT3 Regulatory Module Enhances Rice Pollen Fertility by Mediating Sucrose Allocation to Anthers

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sucrose transport and starch accumulation are crucial carbohydrate metabolic processes in rice, playing essential roles during late pollen development to ensure pollen maturation, fertility and high grain production. However, the molecular mechanisms regulating sucrose transport and starch accumulation during rice pollen development remain ...
Qiuping Li, Chunlong Zhang, Shuaibing Wang, Jin Chen, Yandong Sun, Wenqing Ma, Yu Yong, Qinghui Yang, Lijuan Chen, Jiancheng Wen, Dandan Li   +10 more
wiley   +1 more source