Results 81 to 90 of about 29,074 (248)

Speciation with gene flow

PLANTS, PEOPLE, PLANET, EarlyView.
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long, Xu Zhang, Yue Yu, Gregory L. Owens, Diana J. Rennison, Clarisse Palma‐Silva, Daniel Ortiz‐Barrientos, Loren H. Rieseberg   +7 more
wiley   +1 more source

Impact of plant breeding on the responsiveness of maize and wheat varieties to an arbuscular mycorrhizal fungal symbiont

PLANTS, PEOPLE, PLANET, EarlyView.
Field inoculation with arbuscular mycorrhizal fungi (AMF) offers a promising route to improve sustainable agriculture and food production, yet results are often variable. We investigated the mycorrhizal growth response of maize and wheat varieties recommended for farmers and found substantial variation under greenhouse conditions.
Ido Rog, Marco Malinowski, Dylan Baumann, Raphaël Boussageon, Stefanie Lutz, Marcel G. A. van der Heijden   +5 more
wiley   +1 more source

CKLF‐like MARVEL transmembrane domain‐containing superfamily 8 (CMTM8) promotes Notch signalling to maintain CD8+ T cell‐ and NK cell‐dependent tumour immune escape

British Journal of Pharmacology, EarlyView.
Background and Purpose The CKLF‐like MARVEL transmembrane domain containing superfamily (CMTM) has an important role in tumour immunity. The role of CMTM8 in tumour immune microenvironment (TIME) remains unknown. The aim was to investigate the relationship between CMTM8 and antitumour immunity. Experimental Approach Lentiviral system was established to
Fanglin Li, Longhua Gu, Runqiu Chen, Zhiying Li, Rong Zhang, Chen Chen, Yi Liu, Xinhang Zheng, Yiting Wang, Shanna Wu, Jianhua Sun, Jing Chen, Bingshun Wang, Likun Gong, Yiru Long   +14 more
wiley   +1 more source

Lettuce Genetics: Inheritance, Linkage, and Epistasis [PDF]

Journal of the American Society for Horticultural Science, 1992
Two new lettuce (Luctuca sativa L.) genes are described and named truncated leaf (tn), and sickly (si). A gene for reflexed involucre is identical to that previously described in wild lettuce (L.
openaire   +1 more source

Genetic epistasis regulates amyloid deposition in resilient aging [PDF]

Alzheimer's & Dementia, 2017
AbstractIntroductionThe brain‐derived neurotrophic factor (BDNF) interacts with important genetic Alzheimer's disease (AD) risk factors. Specifically, variants within the SORL1 gene determine BDNF's ability to reduce amyloid β (Aβ) in vitro. We sought to test whether functional BDNF variation interacts with SORL1 genotypes to influence expression and ...
Felsky, Daniel, Xu, Jishu, Chibnik, Lori, Schneider, Julie, Knight, Jo, Kennedy, James L., Bennett, David A., De Jager, Philip L., Voineskos, Aristotle N.   +8 more
openaire   +3 more sources

Genetic and Ecological Management of Pacific Salmon Fisheries for the 21st Century

Fisheries Management and Ecology, EarlyView.
ABSTRACT Based on ecological adaptation theory, tremendous effort is being spent on measures that are eliminating salmon hatcheries and fishing opportunities with the intention of protecting wild runs deemed to be of particular genetic importance to the survival of the species.
Randall E. Brummett, Ian G. Cowx, Devin M. Bartley   +2 more
wiley   +1 more source

Data from: The causes of epistasis in genetic networks

, 2011
Epistasis refers to the non-additive interactions between genes in determining phenotypes. Considerable efforts have shown that, even for a given organism, epistasis may vary both in intensity and sign.
Elena, Santiago F., Macía, Javier, Solé, Ricard V.   +2 more
core   +1 more source

The causes of epistasis [PDF]

, 2011
Since Bateson's discovery that genes can suppress the phenotypic effects of other genes, gene interactions—called epistasis—have been the topic of a vast research effort.
Elena, Santiago F., Cooper, Tim F., Elena Fito, Santiago Fco, Elena, S.F., Santiago F. Elena, Arjan, G. M., de Visser, J.A.G.M., De Visser, J., Tim F. Cooper, J. Arjan G. M. de Visser, Cooper, T.F., de Visser, J. Arjan G. M.   +11 more
core   +1 more source

wtest: an integrated R package for genetic epistasis testing [PDF]

BMC Medical Genomics, 2019
AbstractBackgroundWith the increasing amount of high-throughput genomic sequencing data, there is a growing demand for a robust and flexible tool to perform interaction analysis. The identification of SNP-SNP, SNP-CpG, and higher order interactions helps explain the genetic etiology of human diseases, yet genome-wide analysis for interactions has been ...
Rui Sun, Xiaoxuan Xia, Ka Chun Chong, Benny Chung-Ying Zee, William Ka Kei Wu, Maggie Haitian Wang   +5 more
openaire   +3 more sources

Clinical Implications of Digenic Inheritance and Epistasis in Primary Immunodeficiency Disorders

Frontiers in Immunology, 2018
The existence of epistasis in humans was first predicted by Bateson in 1909. Epistasis describes the non-linear, synergistic interaction of two or more genetic loci, which can substantially modify disease severity or result in entirely new phenotypes ...
Rohan Ameratunga, Rohan Ameratunga, See-Tarn Woon, Vanessa L. Bryant, Vanessa L. Bryant, Richard Steele, Charlotte Slade, Charlotte Slade, Euphemia Yee Leung, Klaus Lehnert   +9 more
doaj   +1 more source