Results 101 to 110 of about 27,549 (205)
Detection of epitasis, additive and dominance variation in rice (Oryza sativa L.) using triple test cross analysis [PDF]
Electronic Journal of Plant Breeding, 2014 An investigation was carried out to detect the epistasis, additive and dominance components of genetic variance for yield and yield attributing traits through triple test cross analysis, involving three testers (P1, P2 and their F1) and ten lines of rice.
N.R. Koli, Chandra Prakash, R.K. Mahawar ,B.L.Kumhar and S.S.Punia
doaj
SIRT Family: Biological Functions and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Applications and limitations of AI tools in enzyme design
Protein Science, Volume 35, Issue 8, August 2026.Abstract Enzymes catalyze various different chemical reactions often with high efficiency and selectivity compared to synthetic catalysts. Advances in protein engineering over the past decades have allowed researchers to design enzymes, improving their catalytic performance and adapting them for specific or entirely novel chemical reactions.
Rosa Teijeiro‐Juiz +6 more
wiley +1 more source
Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening
Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker +3 more
wiley +2 more sources
Protein Science, Volume 35, Issue 8, August 2026.Abstract Deep mutational scanning (DMS) has proven effective for mapping protein–protein interactions (PPIs), but it cannot provide complete coverage of the mutation landscape, particularly for multi‐mutant variants. To address this limitation, we trained machine‐learning (ML) models on previously generated DMS data for a stabilized amyloid precursor ...
Reut Meiri +5 more
wiley +1 more source
Genetics and Molecular Biology, 2013 Epistasis, an additive-by-additive interaction between quantitative trait loci, has been defined as a deviation from the sum of independent effects of individual genes.
Jan Bocianowski
doaj
AP‐1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids
Biology of the Cell, Volume 118, Issue 8, August 2026.We show that in mouse intestinal organoids, AP‐1B is implicated in apical polarity, differentiation in the secretory lineage and proliferation. In particular, we propose that proliferation is controlled by AP‐1B via the mTOR and YAP pathways. Arrows show the functional links that were elucidated in this study, and dotted lines show putative downstream ...
Maela Duclos +5 more
wiley +1 more source
Evolutionary Applications, Volume 19, Issue 8, August 2026.ABSTRACT Soil microbial communities underpin key ecosystem processes, including plant health, nutrient cycling and primary productivity. In agricultural soils, beneficial soil bacteria are often exposed to multiple stressors simultaneously, including fungicides, antibiotics, and warming temperatures. Despite their ecological importance, little is known
Matthew Kelbrick +2 more
wiley +1 more source
Genetic and Ecological Management of Pacific Salmon Fisheries for the 21st Century
Fisheries Management and Ecology, Volume 33, Issue 4, Page 633-645, August 2026.ABSTRACT Based on ecological adaptation theory, tremendous effort is being spent on measures that are eliminating salmon hatcheries and fishing opportunities with the intention of protecting wild runs deemed to be of particular genetic importance to the survival of the species.
Randall E. Brummett +2 more
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 8, Page 4844-4859, August 2026.ABSTRACT Cultivated peanut (Arachis hypogaea L.) is an important oilseed and cash crop, and seed sucrose content (SSC), seed oil content (SOC) and seed protein content (SPC) are key determinants of seed flavour, texture, and overall quality. Identifying quantitative trait loci (QTLs) and candidate genes associated with SSC, SOC and SPC is therefore of ...
Yuzhen Zheng +20 more
wiley +1 more source