Results 101 to 110 of about 37,358 (239)

Do spatially targeted weed management strategies increase risk of herbicide resistance evolution?

open access: yesPest Management Science, EarlyView.
Spray‐buffers reduce the effect of detection inaccuracies in spot spraying. We found a trade‐off between short‐term weed population control efficacy and long‐term prevention of herbicide resistance evolution. Abstract Background Spatially targeted spraying is an alternative to broadcast herbicide application that reduces herbicide use by restricting ...
Hugo Salinas   +3 more
wiley   +1 more source

Yeast Knockout Strain Collection: Driving Functional Genomics, Biotechnological Applications and Human Disease Research

open access: yesYeast, EarlyView.
ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley   +1 more source

SimHOEPI: A resampling simulator for generating single nucleotide polymorphism data with a high‐order epistasis model

open access: yesQuantitative Biology
Epistasis is a ubiquitous phenomenon in genetics, and is considered to be one of main factors in current efforts to unveil missing heritability of complex diseases.
Yahan Li   +4 more
doaj   +1 more source

Beyond Algorithmic Phase Transitions: Integrating Evolutionary Contingency, Biophysical Constraints, and System-Level Organization in Eukaryogenesis. [PDF]

open access: yesFASEB Bioadv
ABSTRACT Understanding the origins and determinants of biological complexity requires integrating theoretical and empirical perspectives across the tree of life. The present work discusses a recent theoretical proposal suggesting that the emergence of eukaryotes can be understood as an algorithmic phase transition governed by universal scaling laws in ...
Salas A.
europepmc   +2 more sources

Advancing FAIR phylogenetics for health threats: a systematic review of SARS‐CoV‐2 research and guidelines for future outbreaks

open access: yesCladistics, EarlyView.
Abstract During the COVID‐19 pandemic, the need for quick public health action often conflicted with the careful methods required in phylogenetics. To explore this, we reviewed 217 SARS‐CoV‐2 studies published from January 2020 to March 2025 in 121 journals.
Omkar Marne, Denis Jacob Machado
wiley   +1 more source

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

open access: yesThe FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo   +8 more
wiley   +1 more source

Performance analysis of novel methods for detecting epistasis

open access: yesBMC Bioinformatics, 2011
Background Epistasis is recognized fundamentally important for understanding the mechanism of disease-causing genetic variation. Though many novel methods for detecting epistasis have been proposed, few studies focus on their comparison.
Shang Junliang   +5 more
doaj   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

open access: yesImmunology, EarlyView.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang   +9 more
wiley   +1 more source

Testing the Domino Theory of Gene Loss in Buchnera aphidicola: The Relevance of Epistatic Interactions

open access: yesLife, 2018
The domino theory of gene loss states that when some particular gene loses its function and cripples a cellular function, selection will relax in all functionally related genes, which may allow for the non-functionalization and loss of these genes.
David J. Martínez-Cano   +3 more
doaj   +1 more source

Genetic Evaluation of Pure Line Laying Hens Based on Crossover Testing Data From Simulated Populations

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Commercial laying hen breeding programs aim to maximize the performance of crossbred animals. However, selection is usually based on data from pure lines raised in controlled nucleus environments, which may not fully predict the yields under commercial conditions.
M. Sánchez‐Diaz   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy