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Epistasis in Neuropsychiatric Disorders
Trends in Genetics, 2017The contribution of epistasis to human disease remains unclear. However, several studies have now identified epistatic interactions between common variants that increase the risk of a neuropsychiatric disorder, while there is growing evidence that genetic interactions contribute to the pathogenicity of rare, multigenic copy-number variants (CNVs) that ...
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Epistasis and intramolecular networks in protein evolution.
Current Opinion in Structural Biology, 2021C. Miton, Karol Buda, N. Tokuriki
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Pleiotropy, epistasis and the genetic architecture of quantitative traits
Nature reviews geneticsT. Mackay, R. Anholt
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Ecology shapes epistasis in a genotype–phenotype–fitness map for stick insect colour
Nature Ecology & Evolution, 2020P. Nosil +5 more
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