Results 131 to 140 of about 351,513 (313)

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Epithelial–mesenchymal transition in pulmonary carcinosarcoma: case report and literature review

Therapeutic Advances in Medical Oncology, 2012
Pulmonary carcinosarcoma is a rare and aggressive neoplasm that has both epithelial and mesenchymal components. We report on a 63-year-old woman who was found to have a right upper-lobe pulmonary carcinosarcoma with metastases to the liver and gastric ...
Vibha T. Thomas, Stacy Hinson, Kartik Konduri   +2 more
doaj   +1 more source

Epithelial-mesenchymal transition: Understanding the basic concept

Journal of Orofacial Sciences, 2012
The epithelial-mesenchymal transition (EMT) is described as a rapid and reversible process of change of cell phenotype seen during embryonic development, organ fibrosis, and tumor progression.
Suresh Babu Ghanta, Neha Nayan, N Govind Raj Kumar, Swetha Pasupuleti   +3 more
doaj   +1 more source

Coal dust nanoparticles induced pulmonary fibrosis by promoting inflammation and epithelial-mesenchymal transition via the NF-κB/NLRP3 pathway driven by IGF1/ROS-mediated AKT/GSK3β signals [PDF]

, 2022
Yinci Zhang, Jiaojiao Liang, Niandie Cao, Jiafeng Gao, Song Li, Xiaolong Tang   +5 more
openalex   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

Advanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi, David Pretzel, Peer Nölte, Kourosh Rezaei, Ulrich S. Schubert, Johannes C. Brendel   +5 more
wiley   +1 more source

Hook1 inhibits malignancy and epithelial–mesenchymal transition in hepatocellular carcinoma

Tumor Biology, 2017
Hook1 is a member of the hook family of coiled-coil proteins, which is recently found to be associated with malignant tumors. However, its biological function in hepatocellular carcinoma is yet unknown.
Xu Sun, Qi Zhang, Wei Chen, Qida Hu, Yu Lou, Qi-Han Fu, Jing-Ying Zhang, Yi-Wen Chen, Long-Yun Ye, Yi Wang, Shang-Zhi Xie, Li-Qiang Hu, Ting-Bo Liang, Xue-Li Bai   +13 more
doaj   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Integrated analysis of single-cell RNA-seq and ATAC-seq in lens epithelial cells: Unveiling the role of ATF6 as a key transcription factor

Genes and Diseases
Lens epithelium, a fundamental biological structure pivotal for maintaining normal vision, can be disrupted, leading to the development of cataracts.
Huiping Lu, Xianyang Liu, Qian Zhou, Ruonan Li, Hangjia Zuo, Ke Hu, Meng Tian, Hong Wang, Jianqiao Li, Na Li, Shengping Hou   +10 more
doaj   +1 more source

GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway

, 2022
Kui Xiang, Hua Yanshan, Zhao Chunmei, Guo Minmin, Yan Wang, Xiaojia Yi   +5 more
openalex   +2 more sources