Results 31 to 40 of about 351,513 (313)

SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma [PDF]

, 2018
Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread.
Bellenghi, Maria, Bottero, Lisabianca, Carè, Alessandra, Felicetti, Federica, Gulino, Alessandro, Mattia, Gianfranco, Petrini, Marina, Pontecorvi, Giada, Puglisi, Rossella   +8 more
core   +1 more source

Sub-Sets of Cancer Stem Cells Differ Intrinsically in Their Patterns of Oxygen Metabolism [PDF]

, 2013
PMCID: PMC3640080This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Adrian Biddle, Anne C. Johannessen, DM Brizel, E Gemenetzidis, E Louie, E Sasabe, E Sasabe, G Dontu, GL Semenza, H Wang, H Zhang, H Zhong, Hannah K. Heywood, HK Heywood, I Papandreou, Ian C. Mackenzie, JP Thiery, JW Kim, LJ Harper, LJ Harper, Luke Gammon, M Al-Hajj, M Diehn, M Wartenberg, ME Prince, MF Clarke, MH Yang, MH Yang, MK Ayrapetov, O Warburg, O Warburg, P van Uden, PB Gupta, PD Sutphin, PJ Kallio, Q Li, R Sullivan, RD Lester, SA Mani, SM Wigfield, SS Prime, T Brabletz, T McFate, Yao Liang Tang   +43 more
core   +10 more sources

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. [PDF]

, 2016
The epithelial-mesenchymal transition (EMT) endows carcinoma cells with phenotypic plasticity that can facilitate the formation of cancer stem cells (CSCs) and contribute to the metastatic cascade.
Banno, Asoka, Bui, Jack D, Chang, Aaron N, Chang, John T, Fisch, Kathleen, Florea, Bogdan I, Garcia, Daniel A, Geurink, Paul P, Kim, Stephanie H, Lopez, Justine, Metz, Patrick J, Ovaa, Huib, Overkleeft, Hermen S, van Baarsel, Eric D, Widjaja, Christella E, Yang, Jing   +15 more
core   +2 more sources

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease [PDF]

, 2009
The events that convert adherent epithelial cells into individual migratory cells that can invade the extracellular matrix are known collectively as epithelial-mesenchymal transition (EMT).
Akitaya, Alkhateeb, Andersson, Barrallo-Gimeno, Bertocchini, Chea, Ciruna, del Barrio, Dixon, Dottori, el Ghouzzi, Favier, Gans, Garcia-Castro, Giehl, Haraguchi, Hervé Acloque, Iwano, Johansson, Kalluri, Katherine Fishwick, Kitajima, Kos, Kwok, Liu, Liu, M. Angela Nieto, Manzanares, Marianne Bronner-Fraser, Martin, Mathieu, Meghan S. Adams, Moreno-Bueno, Nakagawa, Nakaya, Nieto, Peinado, Perea-Gomez, Perez-Pomares, Pijnenborg, Popperl, Sato, Sela-Donenfeld, Sela-Donenfeld, Selleck, Shah, Skromne, Tanimizu, Thiery, Varlet   +49 more
core   +3 more sources

MOESM1 of Pepsin promotes IL-8 signaling-induced epithelialâ mesenchymal transition in laryngeal carcinoma

, 2019
Additional file 1: Table S1. Change in inflammatory cytokine expression of Hep-2 and Tu212 cells exposed to different pepsin concentrations measured using CBA assays. Table S2. Change in inflammatory cytokine expression of Hep-2 and Tu212 cells exposed to pepsin with or without pepstatin measured using CBA assays.
Tan, Jia-Jie, Wang, Lu, Mo, Ting-Ting, Wang, Jie, Wang, Mei-Gui, Li, Xiang-Ping   +5 more
openaire   +1 more source

The Emerging Role of Exosomes in Epithelial–Mesenchymal-Transition in Cancer [PDF]

Frontiers in Oncology, 2014
Metastasis in cancer consists of multiple steps, including epithelial-mesenchymal-transition (EMT), which is characterized by the loss of epithelial-like characteristics and the gain of mesenchymal-like attributes including cell migration and invasion. It is clear that the tumor microenvironment can promote the metastatic cascade and that intercellular
openaire   +4 more sources

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]

, 2016
Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C, CARDINALI, CLAUDIO, GISMONDI, Angela, MORELLI, MARIA BEATRICE, Nabissi, M, Santoni, G., Santoni, M   +6 more
core   +1 more source

MOESM1 of Correlations between chromobox homolog 8 and key factors of epithelial–mesenchymal transition in hepatocellular carcinoma

, 2019
Additional file 1: Table S1. Correlation between CBX8 expression and clinic-pathological characteristics of HCC patients.
Zhu, Xiaonian, Luo, Wei, Bei, Chunhua, Kong, Juan, Zhang, Shidong, Fu, Yuanyuan, Li, Di, Tan, Shengkui   +7 more
openaire   +1 more source

Communication Between Epithelial–Mesenchymal Plasticity and Cancer Stem Cells: New Insights Into Cancer Progression

Frontiers in Oncology, 2021
The epithelial–mesenchymal transition (EMT) is closely associated with the acquisition of aggressive traits by carcinoma cells and is considered responsible for metastasis, relapse, and chemoresistance.
Xiaobo Zheng, Fuzhen Dai, Lei Feng, Hong Zou, Hong Zou, Li Feng, Mingqing Xu, Mingqing Xu   +7 more
doaj   +1 more source

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation [PDF]

, 2016
Plasticity in epithelial tissues relates to processes of embryonic development, tissue fibrosis and cancer progression. Pharmacological modulation of epithelial transitions during disease progression may thus be clinically useful.
Bellomo, C, Bickle, M, Carthy, JM, Gahman, TC, Heldin, A, Heldin, CH, Kardassis, D, Morén, A, Moustakas, A, Shiau, AK, Stöter, M, Vanlandewijck, M, Zerial, M   +12 more
core   +1 more source